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Chapitres
- 00:04Introduction
- 01:30Workflow for Ultrasound M‐Mode or Apical View DICOM Image Analysis and LV Parameter Extraction
- 02:34PAK Finite Element Solver for Fluid‐Structure (FS) Simulations
- 04:30Determination of Ventricular Activation Sequence from ECG Measurement
- 06:27Results: Fibers Direction, Velocity, Pressure Field, and Displacements in the Parametrical LV Model, Simulation of Whole‐Heart Activation, and Maps of Body Surface Potential
- 08:17Conclusion
This protocol demonstrates the workflow of the SILICOFCM platform for automatically generating a parametric model of the left ventricle from patient-specific ultrasound images by applying a multi-scale electromechanical model of the heart. This platform enables in silico clinical trials intended to reduce real clinical trials and maximize positive therapeutic outcomes.
Tags
In Silico Clinical TrialsCardiovascular DiseaseSilico FCM PlatformLeft VentriclePatient-specific Ultrasound ImagesElectromechanical ModelHeartDrug EffectsBoundary ConditionsECGCalcium FunctionHeart MuscleCardiomyopathyHeart FailureCardiac IschemiaArrhythmiaAtrial FibrillationVirtual Population ModuleUltrasound M-ModeApical View WorkflowDICOM FilesGeometryShaded ModelWire Frame ModelInlet And Outlet VelocitiesFinite Element MeshPatient-specific Condition
