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JoVE Journal Immunology and Infection
Hundens tarmorganoider i ett permeabelt stödsystem med dubbla kammare
 
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Hundens tarmorganoider i ett permeabelt stödsystem med dubbla kammare

Article DOI: 10.3791/63612-v • 11:11 min • March 2nd, 2022
March 2nd, 2022 •
1, 1, 2, 3, 2, 3, 4, 5, 2, 2,3, 1,3
1Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, 2Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, 33D Health Solutions Inc., 4Office of New Animal Drug Evaluation, Center for Veterinary Medicine, Food and Drug Administration, 5Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, Food and Drug Administration

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Här presenterar vi ett protokoll som beskriver kulturen av hundens tarmorganoider i ett dubbelkammare, permeabelt stödsystem. Organoid sådd i de permeabla stöden, monolagerunderhållet och efterföljande läkemedelspermeabilitetsexperiment beskrivs.

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Immunologi och infektion utgåva 181 permeabelt stöd dubbelkammare hund organoid tarm stamcell translationell forskning omvänd translationell forskning One Health-initiativ läkemedelsupptäckt läkemedelspermeabilitet
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