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1Marsico Lung Institute / CF Center,The University of North Carolina at Chapel Hill, 2Rheonova, 3Department of Pulmonary and Critical Care Medicine,The University of North Carolina at Chapel Hill, 4Department of Pediatric, Pediatric Pulmonology Division,The University of North Carolina at Chapel Hill
Chapitres
- 00:04Introduction
- 01:22Sputum or Mucus Collection and Storage
- 02:11Sample Preparation
- 03:17Instrument Initialization and Calibration
- 04:21Sample Loading
- 05:49Initiate Biophysical Measurement and Sample Removal
- 06:33Results: Using Benchtop Rheometer to Monitor Changes in Mucus Viscoelasticity
- 08:05Conclusion
As propriedades viscoelásticas do muco desempenham um papel crítico na liberação mucociliaria. No entanto, as técnicas reológicas muco tradicionais requerem abordagens complexas e demoradas. Este estudo fornece um protocolo detalhado para o uso de um reômetro de bancada que pode realizar de forma rápida e confiável medições viscoelásticas.
