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Chapitres
- 00:05Introduction
- 01:00Preparation of Instruments and Intubation of 10-Day-Old Mice
- 03:09Myocardial Infarction Surgery of 10-Day-Old Mice
- 05:13Post-Surgery Assessment of Infarct Size
- 07:04Results: Anesthesia Regimen, Number of Intubation Attempts, and Post-Procedure Survival of 10-Day-Old Mouse Pups
- 08:58Conclusion
Cardiothoracic surgical models in mice >7 days old require intubation, but this is challenging for preadolescent (8-14-day-old) mouse pups and there is little information on anesthetic regimens for intubation. Here, we present dosage regimens of ketamine/xylazine/atropine in 10-day-old C57BL/6J mouse pups that allow endotracheal intubation, while minimizing animal mortality.
