Journal
/
Médecine
/
High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
Journal JoVE
Médecine
Un abonnement à JoVE est nécessaire pour voir ce contenu.  Connectez-vous ou commencez votre essai gratuit.
Journal JoVE Médecine
High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

DOI:
10.3791/64066-v

•

11:09 min

•

December 16, 2022

•

, , , , , ,
1CNR Institute of Clinical Physiology, 2Sant’Anna School of Advanced Studies, 3Fondazione Regione Toscana/CNR “G. Monasterio”

Chapitres

  • 00:05Introduction
  • 01:31Animal Preparation for Positron Emission Tomography (PET)/Computed Tomography (CT) Imaging
  • 02:08PET Tracer Dose Preparation
  • 02:55CT Contrast Agent Preparation
  • 03:35CT Scans
  • 04:34PET Cardiac Analysis
  • 06:21Cine-CT Cardiac Analysis
  • 08:46Results: Morphofunctional and Metabolic Evaluation of the Heart
  • 10:19Conclusion

Summary

Traduction automatique

Traduction automatique

Here, we present an experimental imaging protocol for the quantification of cardiac function and morphology using high-resolution positron emission tomography/computed tomography for small animals. Both mice and rats are considered, discussing the different requirements of computed tomography contrast agents for the two species.

Tags

Cardiac PET/CTSmall Animal ImagingMyocardial InfarctionCardiometabolic DiseasesCardiac MetabolismCardiac FunctionF-18 FDGIomeprolCaudal Vein CannulationBlood SamplingAnesthesiaTemperature MonitoringRespiration MonitoringMotion Artifacts

Article

Embed

AJOUTER À LA PLAYLIST

Usage Statistics

Vidéos Connexes

Basic Surgical Techniques in the Göttingen Minipig: Intubation, Bladder Catheterization, Femoral Vessel Catheterization, and Transcardial Perfusion

Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (FDG-PET/CT)

Protocol for Long Duration Whole Body Hyperthermia in Mice

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers

Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with 18F-FDG

Human Brown Adipose Tissue Depots Automatically Segmented by Positron Emission Tomography/Computed Tomography and Registered Magnetic Resonance Images

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images

Disposable Dosators for Pulmonary Insufflation of Therapeutic Agents to Small Animals

Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function

Tissue Preparation Techniques for Contrast-Enhanced Micro Computed Tomography Imaging of Large Mammalian Cardiac Models with Chronic Disease

Read Article