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Using a Bipolar Electrode to Create a Temporal Lobe Epilepsy Mouse Model by Electrical Kindling of the Amygdala
Journal JoVE
Neurosciences
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Journal JoVE Neurosciences
Using a Bipolar Electrode to Create a Temporal Lobe Epilepsy Mouse Model by Electrical Kindling of the Amygdala
DOI:

09:49 min

June 29, 2022

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Chapitres

  • 00:04Introduction
  • 00:54Fabrication of Electrodes
  • 03:54Slip Ring Connection and Circuit Description
  • 04:34Surgery for Implantation
  • 07:00Electrical Kindling
  • 08:13Results: Temporal Lobe Epilepsy Induced by Electrical Kindling of the Amygdala in a Murine Model
  • 09:18Conclusion

Summary

Traduction automatique

The amygdala plays a key role in temporal lobe epilepsy, which originates in and propagates from this structure. This article provides a detailed description of the fabrication of deep brain electrodes with both recording and stimulating functions. It introduces a model of medial temporal lobe epilepsy originating from the amygdala.

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