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Electromagnetic Controlled Closed-Head Model of Mild Traumatic Brain Injury in Mice
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Journal JoVE Neurosciences
Electromagnetic Controlled Closed-Head Model of Mild Traumatic Brain Injury in Mice

Electromagnetic Controlled Closed-Head Model of Mild Traumatic Brain Injury in Mice

DOI:
10.3791/64556-v

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09:07 min

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September 28, 2022

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, ,
1Spinal Cord & Brain Injury Research Center,University of Kentucky, 2Department of Neuroscience,University of Kentucky, 3Sanders-Brown Center on Aging,University of Kentucky

Chapitres

  • 00:04Introduction
  • 01:01Surgical Setup and Pre-Surgery Procedure
  • 02:45Surgical Procedure
  • 06:39Post-Surgery Care
  • 07:17Results: Characterization of Mild Traumatic Brain Injury in Mice
  • 08:31Conclusion

Summary

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The protocol describes mild traumatic brain injury in a mouse model. In particular, a step-by-step protocol to induce a mild midline closed head injury and the characterization of the animal model is fully explained.

Tags

Keywords: Mild Traumatic Brain InjuryCHI ModelClosed-head InjuryElectromagnetic ImpactorAnimal ModelMouse ModelNeuroimagingNeuropathologyBehavioral ChangesReproducibility

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