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Spontaneous Murine Model of Anaplastic Thyroid Cancer
Journal JoVE
Recherche en cancérologie
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Journal JoVE Recherche en cancérologie
Spontaneous Murine Model of Anaplastic Thyroid Cancer
DOI:

05:39 min

February 03, 2023

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Chapitres

  • 00:04Introduction
  • 01:00Tamoxifen‐Induced TBP Mice
  • 01:31Dissection and Imaging of Mouse Thyroid and Metastatic Tumors
  • 03:35Results: Tumor Growth Assessment in Tamocifen‐Induced TBP Mice
  • 05:10Conclusion

Summary

Traduction automatique

Here, we present a standard pipeline to obtain murine ATC tumors by spontaneous genetically engineered mouse models. Further, we present tumor dynamics and pathological information about the primary and metastasized lesions. This model will help researchers to understand tumorigenesis and facilitate drug discoveries.

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