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Surgical Approach, Challenges, and Resolutions for Uterus Transplantation in Rats
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Médecine
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Journal JoVE Médecine
Surgical Approach, Challenges, and Resolutions for Uterus Transplantation in Rats

Surgical Approach, Challenges, and Resolutions for Uterus Transplantation in Rats

DOI:
10.3791/64757-v

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06:22 min

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April 14, 2023

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, , , ,
1Swiss HPB Laboratory, Department of Visceral & Transplant Surgery,University Hospital Zürich

Chapitres

  • 00:04Introduction
  • 00:49Uterus Retrieval
  • 03:01Syngeneic Uterus Transplantation
  • 04:24Results: Effects of Uterine Transplantation
  • 05:28Conclusion

Summary

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The present protocol describes all the essential steps for successful uterine transplantation (UTx) in rats. The rat model has proven suitable to promote the clinical implementation of UTx; however, rat UTx is a highly complex procedure requiring careful instructions.

Tags

Uterus TransplantationMicrosurgical ProcedureRight Uterine HornCommon Uterine CavityCervixVascular PediclesLaparotomyOrgan Preservation SolutionCommon Iliac ArteryCommon Iliac VeinHeparinXylazineBlunt DissectionAortic BifurcationVena Cava BifurcationStay Suture

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