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Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics
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Médecine
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Journal JoVE Médecine
Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics

Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics

DOI:
10.3791/64850-v

•

12:09 min

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April 19, 2024

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, ,
1Faculdade de Medicina da,Universidade de São Paulo

Chapitres

  • 00:00Introduction
  • 00:54Anesthesia and animal preparation
  • 01:48Intraoperative mechanical ventilation
  • 02:49Tissue dissection and orotracheal cannula exchange
  • 03:49Animal euthanasia
  • 04:42Cardiopulmonary preparation
  • 05:22Mechanical ventilation inside an acrylic box
  • 06:07Alveolar recruitment maneuver
  • 06:57Cardiopulmonary maintenance
  • 07:48Representative Results
  • 08:53Conclusion

Summary

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Traduction automatique

We present an ex vivo pig lung model for the demonstration of pulmonary mechanics and alveolar recruitment maneuvers for teaching purposes. The lungs can be used for more than one day (up to five days) with minimal changes in pulmonary mechanics variables.

Tags

Ex Vivo Porcine ModelLung MechanicsMechanical VentilationRespiratory FailureAnesthesiaTracheal IntubationVentilator SettingsTidal VolumeRespiratory RateEnd-tidal CO2Thoracic CavityTracheal Incision

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