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En silikosemodel med mus etableret ved gentagen indånding af krystallinsk silikatstøv
 
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En silikosemodel med mus etableret ved gentagen indånding af krystallinsk silikatstøv

Article DOI: 10.3791/64862-v • 10:45 min • January 6th, 2023
January 6th, 2023 •
*1,2,3,4, *1,2,3,4, 1,3,4, 1,4, 1,4, 1,4, 1,2,3,4, 1,2,3,4
1Key Laboratory of Industrial Dust Control and Occupational Health of the Ministry of Education, Anhui University of Science and Technology, 2Key Laboratory of Industrial Dust Deep Reduction and Occupational Health and Safety of Anhui Higher Education Institutes, Anhui University of Science and Technology, 3Anhui Province Engineering Laboratory of Occupational Health and Safety, 4School of Medicine, Department of Medical Frontier Experimental Center, Anhui University of Science and Technology
* These authors contributed equally

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Denne protokol beskriver en metode til etablering af en musemodel af silikose gennem gentagen eksponering for silicasuspensioner via et næsedrop. Denne model kan effektivt, bekvemt og fleksibelt efterligne den patologiske proces af human silikose med høj repeterbarhed og økonomi.

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Medicin udgave 191 musemodel indånding patofysiologi screening behandling kliniske symptomer akut/kronisk transformationsproces procedurer CSD-pulver saltvandssuspension ultralydsvandbad anæstesi aspiration indånding af næsebor musebur
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