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Monitoraggio della soglia elettrica a circuito chiuso in tempo reale open source per la ricerca traslazionale del dolore
This content is Free Access.
1Anaesthesia, Pain, and Critical Care Sciences, School of Physiology, Pharmacology, & Neuroscience,University of Bristol, 2Eli Lilly and Company, 3Department of Computer Science,University of Bristol, 4Department of Aerospace Engineering,University of Bristol, 5Research Computing,University of Bristol
Chapitres
- 00:04Introduction
- 01:29Assembly of the Recording and Stimulating Apparatus
- 03:27Software Setup and Identification and Phenotyping of Peripheral Neurons
- 05:43Latency and Electrical Threshold Tracking
- 08:00Results: Electrical Threshold Tracking of Single‐Neuron Action Potentials
- 09:43Conclusion
APTrack è un plugin software sviluppato per la piattaforma Open Ephys che consente la visualizzazione dei dati in tempo reale e il monitoraggio della soglia elettrica a circuito chiuso dei potenziali d'azione neuronali. Abbiamo usato con successo questo in microneurografia per nocicettori umani in fibra C e nocicettori in fibra C e fibra Aδ di topo.
Tags
Open-sourceReal-timeClosed-loopElectrical Threshold TrackingTranslational Pain ResearchNociceptor SensitizationAutomated Electrical Threshold TrackingNociceptor ExcitabilityBiomarkerAP TrackElectrophysiologyOptogeneticsAcquisition BoardIO BoardIntan RHD Recording HeadstagePulse PalConstant Current StimulatorStepper Motor Control BoardCustom Mounting BracketBarrel Adapter
