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A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes
Journal JoVE
Médecine
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Journal JoVE Médecine
A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes

A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes

DOI:
10.3791/64914-v

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05:18 min

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February 17, 2023

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, , , , , ,
1College of Nursing,Chengdu University of Traditional Chinese Medicine

Chapitres

  • 00:04Introduction
  • 01:04Induction of Type 1 Diabetes Mellitus (T1DM) Model
  • 02:21Construction of the Wound Model
  • 03:18Results: Wound Healing Study in Type I Diabetes Mellitus
  • 04:51Conclusion

Summary

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Traduction automatique

The streptozotocin-induced diabetic wound model in male SD rats is currently the most widely used model for studying wound healing in type I diabetes mellitus. This protocol describes the methods used to construct this model. It also presents and addresses potential challenges and examines the progression and angiogenic characteristics of diabetic wounds.

Tags

Keywords: Rat Wound ModelType 1 DiabetesStreptozotocinChronic Diabetic WoundsWound HealingAngiogenesisBlood Glucose MeasurementSkin ShavingDepilatory CreamSkin DisinfectionSkin IncisionWound Dressing

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