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Automated Protein Crystallization and Real-Time Data Collection

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Author Spotlight: Advancing Protein Structure Analysis for Drug Development

Journal JoVE
Biochimie

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Journal JoVE Biochimie

Crystallization and In Situ Room Temperature Data Collection Using the Crystallization Facility at Harwell and Beamline VMXi, Diamond Light Source

Author Spotlight: Advancing Protein Structure Analysis for Drug Development

Automated Protein Crystallization and Real-Time Data Collection

DOI:

10.3791/65964-v

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00:48 min

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March 08, 2024

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James Sandy, Halina Mikolajek², Amy J. Thompson, Juan Sanchez-Weatherby, Michael A Hough²

¹Diamond Light Source Ltd,Harwell Science and Innovation Campus, ²Research Complex at Harwell,Harwell Science and Innovation Campus

Tags

Crystallization In Situ Room Temperature Data Collection Harwell Crystallization Facility Diamond Light Source Beamline VMXi Protein Structure Determination Cryo-free Data Collection Serial Crystallography Drug Development Fragment Screening Robotic Protein Crystallization Machine Learning Queue-based Data Collection Data Merging Structural Biology

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