Philip Morris Research Laboratories Pte. Ltd. 1 article published in JoVE Engineering Use of Capillary Aerosol Generator in Continuous Production of Controlled Aerosol for Non-Clinical Studies Didier Goedertier1, Sandra Schorderet Weber1, Francesco Lucci1, Tom Lee2, Wei Teck Tan2, Falk Radtke1, Subash Krishnan2, Patrick Vanscheeuwijck1, Arkadiusz K. Kuczaj1,3, Julia Hoeng1 1PMI R&D, Philip Morris Products S.A., 2PMI R&D, Philip Morris Research Laboratories Pte. Ltd., 3Applied Mathematics, University of Twente The protocol describes the settings and use of a capillary aerosol generator for continuous production of controlled aerosol from a multispecies liquid solution, suitable for steady large-volume aerosol delivery (e.g., in vivo inhalation studies).