Campbell Family Mental Health Research Institute of CAMH 2 articles published in JoVE Neuroscience BS3 Chemical Crosslinking Assay: Evaluating the Effect of Chronic Stress on Cell Surface GABAA Receptor Presentation in the Rodent Brain Akiko Sumitomo1, Runhao Zhou1,2, Thomas Prevot1,3, Etienne Sibille1,2,3, Toshifumi Tomoda1,3 1Centre for Addiction and Mental Health (CAMH), Campbell Family Mental Health Research Institute, 2Department of Pharmacology and Toxicology, University of Toronto, 3Department of Psychiatry, University of Toronto The BS3 chemical crosslinking assay reveals reduced cell surface GABAA receptor expression in mouse brains under chronic psychosocial stress conditions. Behavior Handling Techniques to Reduce Stress in Mice Michael Marcotte1, Ashley Bernardo1,2, Nathaniel Linga3, Carmina A. Pérez-Romero4, Jean-Louis Guillou5, Etienne Sibille1,2,3, Thomas D. Prevot1,2 1Campbell Family Mental Health Research Institute of CAMH, 2Department of Psychiatry, University of Toronto, 3Department of Pharmacology and Toxicology, University of Toronto, 4Departamento de Investigación, Universidad Central de Queretaro, 5Centre National de la Recherche Scientifique, UMR 5287, Institut de Neurosciences Cognitives et Intégratives d'Aquitaine, Université de Bordeaux This paper describes a handling technique in mice, the 3D-handling technique, which facilitates routine handling by reducing anxiety-like behaviors and presents details on two existing related techniques (tunnel and tail handling).