Future House 1 article published in JoVE Bioengineering A Practical Guide to Phage- and Robotics-Assisted Near-Continuous Evolution Samir Aoudjane1, Stefan Golas2, Osaid Ather1, Michael J. Hammerling3, Erika DeBenedictis1 1The Francis Crick Institute, 2Massachusetts Institute of Technology, 3Future House Phage- and Robotics-assisted Near-continuous Evolution (PRANCE) is a technique for rapid, robust protein evolution. Robotics allows the parallelization of experiments, real-time monitoring, and feedback control.