Cristian Coarfa

Publications

• Leveraging Integrated RNA Sequencing to Decipher Adrenomedullin's Protective Mechanisms in Experimental Bronchopulmonary Dysplasia
  Genes. Jun, 2024  |   Pubmed ID: 38927741
• is a Synthetic-lethal Target in -mutant Leukemia Cells
  ELife. Jun, 2024  |   Pubmed ID: 38896450
• Restrains an Oncogenic Epigenetic Circuit in AT2 Cells to Prevent Ectopic Formation of Fibrogenic Transitional Cell Intermediates and Pulmonary Fibrosis
  BioRxiv : the Preprint Server for Biology. May, 2024  |   Pubmed ID: 38826218
• Altered Extracellular Matrix-Related Pathways Accelerate the Transition from Normal to Pre-Fibroid Myometrium in Black Women
  American Journal of Obstetrics and Gynecology. May, 2024  |   Pubmed ID: 38825029
• The Maternal and Infant Environmental Health Riskscape Study of Perinatal Disparities in Greater Houston: Rationale, Study Design and Participant Profiles
  Frontiers in Reproductive Health. 2024  |   Pubmed ID: 38712340
• Identification of an Early Survival Prognostic Gene Signature for Localized Osteosarcoma Patients
  Scientific Reports. Mar, 2024  |   Pubmed ID: 38538763
• Temporal Dynamics of BMP/Nodal Ratio Drive Tissue-specific Gastrulation Morphogenesis
  BioRxiv : the Preprint Server for Biology. Feb, 2024  |   Pubmed ID: 38370754
• Distinct Amino Acid Profile Characterizes Youth With or at Risk for Type 2 Diabetes
  Diabetes. Apr, 2024  |   Pubmed ID: 38215171
• Genome-wide P63-Target Gene Analyses Reveal TAp63/NRF2-Dependent Oxidative Stress Responses
  Cancer Research Communications. Feb, 2024  |   Pubmed ID: 38165157
• D-Mannose Reduces Cellular Senescence and NLRP3/GasderminD/IL-1β-driven Pyroptotic Uroepithelial Cell Shedding in the Murine Bladder
  Developmental Cell. Jan, 2024  |   Pubmed ID: 38101412
• Adipose Triglyceride Lipase Is a Therapeutic Target in Advanced Prostate Cancer That Promotes Metabolic Plasticity
  Cancer Research. Mar, 2024  |   Pubmed ID: 38038968
• Metabolomic Rewiring Promotes Endocrine Therapy Resistance in Breast Cancer
  Cancer Research. Jan, 2024  |   Pubmed ID: 37906431
• Circadian Dysfunction Induces NAFLD-related Human Liver Cancer in a Mouse Model
  Journal of Hepatology. Feb, 2024  |   Pubmed ID: 37890720
• is a Synthetic Lethal Target in -mutant Leukemia Cells
  BioRxiv : the Preprint Server for Biology. Jan, 2024  |   Pubmed ID: 37693622
• Infant and Adult Human Intestinal Enteroids Are Morphologically and Functionally Distinct
  BioRxiv : the Preprint Server for Biology. Feb, 2024  |   Pubmed ID: 37292968
• Human Intestinal Organoids from Cronkhite-Canada Syndrome Patients Reveal Link Between Serotonin and Proliferation
  The Journal of Clinical Investigation. Nov, 2023  |   Pubmed ID: 37909332
• TGFβ Signaling Links Early Life Endocrine-disrupting Chemicals Exposure to Suppression of Nucleotide Excision Repair in Rat Myometrial Stem Cells
  Cellular and Molecular Life Sciences : CMLS. Sep, 2023  |   Pubmed ID: 37689587
• Multiomic Investigations into Lung Health and Disease
  Microorganisms. Aug, 2023  |   Pubmed ID: 37630676
• Loss of MicroRNA-30a and Sex-specific Effects on the Neonatal Hyperoxic Lung Injury
  Biology of Sex Differences. Aug, 2023  |   Pubmed ID: 37553579
• Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study
  Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Oct, 2023  |   Pubmed ID: 37530747
• Loss of Cytochrome P450 (CYP)1B1 Mitigates Hyperoxia Response in Adult Mouse Lung by Reprogramming Metabolism and Translation
  Redox Biology. Aug, 2023  |   Pubmed ID: 37348155
• TGFβ Signaling Links Early-life Endocrine-disrupting Chemicals Exposure to Suppression of Nucleotide Excision Repair in Rat Myometrial Stem Cells
  Research Square. Jun, 2023  |   Pubmed ID: 37333266
• MYC Regulates CSF1 Expression Via MicroRNA 17/20a to Modulate Tumor-associated Macrophages in Osteosarcoma
  JCI Insight. Jul, 2023  |   Pubmed ID: 37279073
• Functional Genomic Analysis of Non-canonical DNA Regulatory Elements of the Aryl Hydrocarbon Receptor
  BioRxiv : the Preprint Server for Biology. May, 2023  |   Pubmed ID: 37205451
• TRAF4-mediated Nonproteolytic Ubiquitination of Androgen Receptor Promotes Castration-resistant Prostate Cancer
  Proceedings of the National Academy of Sciences of the United States of America. May, 2023  |   Pubmed ID: 37155905
• Evolution of Cisplatin Resistance Through Coordinated Metabolic Reprogramming of the Cellular Reductive State
  British Journal of Cancer. Jun, 2023  |   Pubmed ID: 37012319
• A Human Stem Cell-derived Neuronal Model of Morphine Exposure Reflects Brain Dysregulation in Opioid Use Disorder: Transcriptomic and Epigenetic Characterization of Postmortem-derived IPSC Neurons
  Frontiers in Psychiatry. 2023  |   Pubmed ID: 36873219
• Transcriptome, Proteome, and Protein Synthesis Within the Intracellular Cytomatrix
  IScience. Feb, 2023  |   Pubmed ID: 36824274
• Modeling Ewing Sarcoma Lung Metastasis
  Current Protocols. Feb, 2023  |   Pubmed ID: 36799651
• PD-L1 Translocation to the Plasma Membrane Enables Tumor Immune Evasion Through MIB2 Ubiquitination
  The Journal of Clinical Investigation. Feb, 2023  |   Pubmed ID: 36719382
• Systemic Interindividual Epigenetic Variation in Humans is Associated with Transposable Elements and Under Strong Genetic Control
  Genome Biology. Jan, 2023  |   Pubmed ID: 36631879
• Differential Co-expression Networks of the Gut Microbiota Are Associated with Depression and Anxiety Treatment Resistance Among Psychiatric Inpatients
  Progress in Neuro-psychopharmacology & Biological Psychiatry. Jan, 2023  |   Pubmed ID: 36122838
• Integrative Metabolomics and Transcriptomics Analysis Reveals Novel Therapeutic Vulnerabilities in Lung Cancer
  Cancer Medicine. Jan, 2023  |   Pubmed ID: 35676822
• Patients with Lung Cancer of Different Racial Backgrounds Harbor Distinct Immune Cell Profiles
  Cancer Research Communications. Aug, 2022  |   Pubmed ID: 36923308
• MicroRNA-mRNA Networks Are Dysregulated in Opioid Use Disorder Postmortem Brain: Further Evidence for Opioid-induced Neurovascular Alterations
  Frontiers in Psychiatry. 2022  |   Pubmed ID: 36713930
• LncRNA PVT-1 Promotes Osteosarcoma Cancer Stem-like Properties Through Direct Interaction with TRIM28 and TSC2 Ubiquitination
  Oncogene. Dec, 2022  |   Pubmed ID: 36348010
• The Rheumatoid Arthritis Drug Auranofin Lowers Leptin Levels and Exerts Antidiabetic Effects in Obese Mice
  Cell Metabolism. Dec, 2022  |   Pubmed ID: 36243005
• Sex-specific Epigenetic Development in the Mouse Hypothalamic Arcuate Nucleus Pinpoints Human Genomic Regions Associated with Body Mass Index
  Science Advances. Sep, 2022  |   Pubmed ID: 36170368
• Plasma Protein Biomarkers for Primary Graft Dysfunction After Lung Transplantation: a Single-center Cohort Analysis
  Scientific Reports. Sep, 2022  |   Pubmed ID: 36167867
• Histopathologic and Transcriptomic Phenotypes of a Conditional RANKL Transgenic Mouse Thymus
  Cytokine. Dec, 2022  |   Pubmed ID: 36099756
• Deletion of the Gene in Fibroblasts Causes Senescence-associated Dilated Cardiomyopathy by Activating the Double-stranded DNA Damage Response and Induction of Senescence-associated Secretory Phenotype
  The Journal of Cardiovascular Aging. Jul, 2022  |   Pubmed ID: 35891706
• Early Systemic Glycolytic Shift After Aneurysmal Subarachnoid Hemorrhage is Associated with Functional Outcomes
  Neurocritical Care. Dec, 2022  |   Pubmed ID: 35799091
• MYCN-driven Fatty Acid Uptake is a Metabolic Vulnerability in Neuroblastoma
  Nature Communications. Jun, 2022  |   Pubmed ID: 35764645
• The Prostate Cancer Androgen Receptor Cistrome in African American Men Associates with Upregulation of Lipid Metabolism and Immune Response
  Cancer Research. Aug, 2022  |   Pubmed ID: 35731919
• MAB21L4 Deficiency Drives Squamous Cell Carcinoma Via Activation of RET
  Cancer Research. Sep, 2022  |   Pubmed ID: 35705526
• Calcium/calmodulin-dependent Protein Kinase Kinase 2 Regulates Hepatic Fuel Metabolism
  Molecular Metabolism. Aug, 2022  |   Pubmed ID: 35562082
• High-throughput Profiling of Histone Post-translational Modifications and Chromatin Modifying Proteins by Reverse Phase Protein Array
  Journal of Proteomics. Jun, 2022  |   Pubmed ID: 35489683
• Concerted Type I Interferon Signaling in Microglia and Neural Cells Promotes Memory Impairment Associated with Amyloid β Plaques
  Immunity. May, 2022  |   Pubmed ID: 35443157
• Cistrome and Transcriptome Analysis Identifies Unique Androgen Receptor (AR) and AR-V7 Splice Variant Chromatin Binding and Transcriptional Activities
  Scientific Reports. Mar, 2022  |   Pubmed ID: 35354884
• Metabolome and Microbiome Multi-omics Integration from a Murine Lung Inflammation Model of Bronchopulmonary Dysplasia
  Pediatric Research. Dec, 2022  |   Pubmed ID: 35338351
• Author Correction: ΔNp63 Regulates a Common Landscape of Enhancer Associated Genes in Non-small Cell Lung Cancer
  Nature Communications. Mar, 2022  |   Pubmed ID: 35338160
• Increased DNA Methylation, Cellular Senescence and Premature Epigenetic Aging in Guinea Pigs and Humans with Tuberculosis
  Aging. Mar, 2022  |   Pubmed ID: 35256539
• ISA101 and Nivolumab for HPV-16 Cancer: Updated Clinical Efficacy and Immune Correlates of Response
  Journal for Immunotherapy of Cancer. Feb, 2022  |   Pubmed ID: 35193933
• K-Ras and P53 Mouse Model with Molecular Characteristics of Human Rhabdomyosarcoma and Translational Applications
  Disease Models & Mechanisms. Feb, 2022  |   Pubmed ID: 35174853
• Gene Expression Signatures Identify Biologically and Clinically Distinct Tuberculosis Endotypes
  The European Respiratory Journal. Sep, 2022  |   Pubmed ID: 35169026
• ΔNp63 Regulates a Common Landscape of Enhancer Associated Genes in Non-small Cell Lung Cancer
  Nature Communications. Feb, 2022  |   Pubmed ID: 35105868
• Characterization of the COPD Alveolar Niche Using Single-cell RNA Sequencing
  Nature Communications. Jan, 2022  |   Pubmed ID: 35078977
• MiR-181a Promotes Multiple Protumorigenic Functions by Targeting TGFβR3
  The Journal of Investigative Dermatology. Jul, 2022  |   Pubmed ID: 34890627
• Correction To: Hormonal Modulation of ESR1 Mutant Metastasis
  Oncogene. Jan, 2022  |   Pubmed ID: 34782721
• The EP300/TP53 Pathway, a Suppressor of the Hippo and Canonical WNT Pathways, is Activated in Human Hearts with Arrhythmogenic Cardiomyopathy in the Absence of Overt Heart Failure
  Cardiovascular Research. May, 2022  |   Pubmed ID: 34132777
• Single-cell Sequencing of Rotavirus-infected Intestinal Epithelium Reveals Cell-type Specific Epithelial Repair and Tuft Cell Infection
  Proceedings of the National Academy of Sciences of the United States of America. 11, 2021  |   Pubmed ID: 34732579
• Nuclear S-nitrosylation Impacts Tissue Regeneration in Zebrafish
  Nature Communications. Nov, 2021  |   Pubmed ID: 34725362
• Tuberculosis Endotypes to Guide Stratified Host-directed Therapy
  Med (New York, N.Y.). Mar, 2021  |   Pubmed ID: 34693385
• Inhibition of GATA2 in Prostate Cancer by a Clinically Available Small Molecule
  Endocrine-related Cancer. Nov, 2021  |   Pubmed ID: 34636746
• Endothelium-specific Depletion of LRP1 Improves Glucose Homeostasis Through Inducing Osteocalcin
  Nature Communications. Sep, 2021  |   Pubmed ID: 34489478
• Author Correction: Therapeutically Actionable Signaling Node to Rescue AURKA Driven Loss of Primary Cilia in VHL-deficient Cells
  Scientific Reports. Aug, 2021  |   Pubmed ID: 34462545
• CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis Via Metabolic Reprogramming
  Advanced Science (Weinheim, Baden-Wurttemberg, Germany). Oct, 2021  |   Pubmed ID: 34365742
• Memory and Naïve Gamma Delta Regulatory T-cell Gene Expression in the First 24-weeks of Peanut Oral Immunotherapy
  Clinical Immunology (Orlando, Fla.). Sep, 2021  |   Pubmed ID: 34365017
• A Noncoding RNA Modulator Potentiates Phenylalanine Metabolism in Mice
  Science (New York, N.Y.). Aug, 2021  |   Pubmed ID: 34353949
• A Machine Learning Case-control Classifier for Schizophrenia Based on DNA Methylation in Blood
  Translational Psychiatry. Aug, 2021  |   Pubmed ID: 34341337
• High Potency STING Agonists Engage Unique Myeloid Pathways to Reverse Pancreatic Cancer Immune Privilege
  Journal for Immunotherapy of Cancer. Aug, 2021  |   Pubmed ID: 34341132
• Use of Human Tissue Stem Cell-derived Organoid Cultures to Model Enterohepatic Circulation
  American Journal of Physiology. Gastrointestinal and Liver Physiology. 09, 2021  |   Pubmed ID: 34288725
• Effect of Substrate Stiffness on Human Intestinal Enteroids' Infectivity by Enteroaggregative Escherichia Coli
  Acta Biomaterialia. 09, 2021  |   Pubmed ID: 34280559
• Esomeprazole Enhances the Effect of Ionizing Radiation to Improve Tumor Control
  Oncotarget. Jul, 2021  |   Pubmed ID: 34262645
• Early Detection of Myocardial Changes with and Without Dexrazoxane Using Serial Magnetic Resonance Imaging in a Pre-clinical Mouse Model
  Cardio-oncology (London, England). Jun, 2021  |   Pubmed ID: 34134789
• A Wnt-Independent LGR4-EGFR Signaling Axis in Cancer Metastasis
  Cancer Research. Sep, 2021  |   Pubmed ID: 34099494
• Effect of Sex Chromosomes Versus Hormones in Neonatal Lung Injury
  JCI Insight. Jul, 2021  |   Pubmed ID: 34061778
• Perspectives for Systems Biology in the Management of Tuberculosis
  European Respiratory Review : an Official Journal of the European Respiratory Society. Jun, 2021  |   Pubmed ID: 34039674
• Reverse-Phase Protein Array: Technology, Application, Data Processing, and Integration
  Journal of Biomolecular Techniques : JBT. Apr, 2021  |   Pubmed ID: 34025221
• Superior Efficacy of Co-targeting GFI1/KDM1A and BRD4 Against AML and Post-MPN Secondary AML Cells
  Blood Cancer Journal. May, 2021  |   Pubmed ID: 34016956
• Neuronal SETD2 Activity Links Microtubule Methylation to an Anxiety-like Phenotype in Mice
  Brain : a Journal of Neurology. Sep, 2021  |   Pubmed ID: 34014281
• Therapeutically Actionable Signaling Node to Rescue AURKA Driven Loss of Primary Cilia in VHL-deficient Cells
  Scientific Reports. May, 2021  |   Pubmed ID: 34002003
• Reverse Phase Protein Array Reveals Correlation of Retinoic Acid Metabolism With Cardiomyopathy in Friedreich's Ataxia
  Molecular & Cellular Proteomics : MCP. 2021  |   Pubmed ID: 33991687
• Author Correction: Androgen Receptor and Its Splice Variant, AR-V7, Differentially Induce MRNA Splicing in Prostate Cancer Cells
  Scientific Reports. May, 2021  |   Pubmed ID: 33976356
• Plasma MiRNA Biomarkers in Limited Volume Samples for Detection of Early-stage Pancreatic Cancer
  Cancer Prevention Research (Philadelphia, Pa.). Jul, 2021  |   Pubmed ID: 33893071
• A Cytoskeletal Function for PBRM1 Reading Methylated Microtubules
  Science Advances. Apr, 2021  |   Pubmed ID: 33811077
• A Phase I Dose-Escalation Study to Evaluate the Safety and Tolerability of Evofosfamide in Combination with Ipilimumab in Advanced Solid Malignancies
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2021  |   Pubmed ID: 33771853
• BET Proteolysis Targeted Chimera-based Therapy of Novel Models of Richter Transformation-diffuse Large B-cell Lymphoma
  Leukemia. Sep, 2021  |   Pubmed ID: 33654205
• Altered Metabolic and Inflammatory Transcriptomics After Cardiac Surgery in Neonates with Congenital Heart Disease
  Scientific Reports. Mar, 2021  |   Pubmed ID: 33654130
• Reverse-Phase Protein Array: Technology, Application, Data Processing, and Integration
  Journal of Biomolecular Techniques : JBT. Jan, 2021  |   Pubmed ID: 33584151
• Constitutive Activation of Mitogen-activated Protein Kinase Kinase (MEK1) in Ileal Enterocytes Leads to Dysplasia and a Predisposition to Cancer
  American Journal of Physiology. Gastrointestinal and Liver Physiology. Mar, 2021  |   Pubmed ID: 33470189
• Androgen Receptor and Its Splice Variant, AR-V7, Differentially Induce MRNA Splicing in Prostate Cancer Cells
  Scientific Reports. Jan, 2021  |   Pubmed ID: 33446905
• P21-activated Kinases As Viable Therapeutic Targets for the Treatment of High-risk Ewing Sarcoma
  Oncogene. Feb, 2021  |   Pubmed ID: 33414491
• Hormonal Modulation of ESR1 Mutant Metastasis
  Oncogene. Feb, 2021  |   Pubmed ID: 33323970
• Isoform-specific Activities of Androgen Receptor and Its Splice Variants in Prostate Cancer Cells
  Endocrinology. Mar, 2021  |   Pubmed ID: 33300995
• RON Signalling Promotes Therapeutic Resistance in ESR1 Mutant Breast Cancer
  British Journal of Cancer. Jan, 2021  |   Pubmed ID: 33257837
• Targeting PAK4 Inhibits Ras-Mediated Signaling and Multiple Oncogenic Pathways in High-Risk Rhabdomyosarcoma
  Cancer Research. Jan, 2021  |   Pubmed ID: 33168646
• Haploinsufficiency of Tmem43 in Cardiac Myocytes Activates the DNA Damage Response Pathway Leading to a Late-onset Senescence-associated Pro-fibrotic Cardiomyopathy
  Cardiovascular Research. Sep, 2021  |   Pubmed ID: 33070193
• An Actin-WHAMM Interaction Linking SETD2 and Autophagy
  Biochemical and Biophysical Research Communications. Jun, 2021  |   Pubmed ID: 33036756
• Coagulopathy in Malnourished Mice Is Sexually Dimorphic and Regulated by Nutrient-Sensing Nuclear Receptors
  Hepatology Communications. Dec, 2020  |   Pubmed ID: 33305154
• Integrative Transcriptomic Analysis for Linking Acute Stress Responses to Squamous Cell Carcinoma Development
  Scientific Reports. Oct, 2020  |   Pubmed ID: 33057049
• Pan-cancer Analysis Reveals TAp63-regulated Oncogenic LncRNAs That Promote Cancer Progression Through AKT Activation
  Nature Communications. Oct, 2020  |   Pubmed ID: 33056990
• STAT1 Dissociates Adipose Tissue Inflammation From Insulin Sensitivity in Obesity
  Diabetes. Dec, 2020  |   Pubmed ID: 32994273
• Enteroaggregative E. Coli Adherence to Human Heparan Sulfate Proteoglycans Drives Segment and Host Specific Responses to Infection
  PLoS Pathogens. 09, 2020  |   Pubmed ID: 32986782
• Epigenetic Response to Hyperoxia in the Neonatal Lung is Sexually Dimorphic
  Redox Biology. Oct, 2020  |   Pubmed ID: 32961439
• Human Norovirus Exhibits Strain-specific Sensitivity to Host Interferon Pathways in Human Intestinal Enteroids
  Proceedings of the National Academy of Sciences of the United States of America. 09, 2020  |   Pubmed ID: 32907944
• Correction: Epigenetic Loss of AOX1 Expression Via EZH2 Leads to Metabolic Deregulations and Promotes Bladder Cancer Progression
  Oncogene. Oct, 2020  |   Pubmed ID: 32820250
• Large-scale Discovery of Male Reproductive Tract-specific Genes Through Analysis of RNA-seq Datasets
  BMC Biology. Aug, 2020  |   Pubmed ID: 32814578
• Identification of Genes and Pathways Regulated by Lamin A in Heart
  Journal of the American Heart Association. Aug, 2020  |   Pubmed ID: 32805188
• Targets Gene Networks That Promote Browning of Human and Mouse Adipocytes
  American Journal of Physiology. Endocrinology and Metabolism. Oct, 2020  |   Pubmed ID: 32799658
• Identification of Cell Type-specific Methylation Signals in Bulk Whole Genome Bisulfite Sequencing Data
  Genome Biology. Jul, 2020  |   Pubmed ID: 32605651
• Acquisition of Cisplatin Resistance Shifts Head and Neck Squamous Cell Carcinoma Metabolism Toward Neutralization of Oxidative Stress
  Cancers. Jun, 2020  |   Pubmed ID: 32599707
• BET Bromodomain Inhibition Attenuates Cardiac Phenotype in Myocyte-specific Lamin A/C-deficient Mice
  The Journal of Clinical Investigation. Sep, 2020  |   Pubmed ID: 32484798
• Vitamin D Actions in Neurons Require the PI3K Pathway for Both Enhancing Insulin Signaling and Rapid Depolarizing Effects
  The Journal of Steroid Biochemistry and Molecular Biology. 06, 2020  |   Pubmed ID: 32408067
• Epigenome Environment Interactions Accelerate Epigenomic Aging and Unlock Metabolically Restricted Epigenetic Reprogramming in Adulthood
  Nature Communications. May, 2020  |   Pubmed ID: 32385268
• Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma
  Cancer Cell. May, 2020  |   Pubmed ID: 32359397
• Estrogen Receptor-α Expressing Neurons in the Ventrolateral VMH Regulate Glucose Balance
  Nature Communications. 05, 2020  |   Pubmed ID: 32358493
• BCL9/STAT3 Regulation of Transcriptional Enhancer Networks Promote DCIS Progression
  NPJ Breast Cancer. 2020  |   Pubmed ID: 32352029
• Discovery, Structure-Activity Relationship, and Biological Activity of Histone-Competitive Inhibitors of Histone Acetyltransferases P300/CBP
  Journal of Medicinal Chemistry. May, 2020  |   Pubmed ID: 32314924
• Spatiotemporal Regulation of ΔNp63 by TGFβ-Regulated MiRNAs Is Essential for Cancer Metastasis
  Cancer Research. Jul, 2020  |   Pubmed ID: 32312834
• TAp63-Regulated MiRNAs Suppress Cutaneous Squamous Cell Carcinoma Through Inhibition of a Network of Cell-Cycle Genes
  Cancer Research. Jun, 2020  |   Pubmed ID: 32156775
• DNA Hypermethylation During Tuberculosis Dampens Host Immune Responsiveness
  The Journal of Clinical Investigation. Jun, 2020  |   Pubmed ID: 32125282
• Targeting Oncogenic Super Enhancers in MYC-Dependent AML Using a Small Molecule Activator of NR4A Nuclear Receptors
  Scientific Reports. Feb, 2020  |   Pubmed ID: 32071334
• Mechanistic Basis and Efficacy of Targeting the β-catenin-TCF7L2-JMJD6-c-Myc Axis to Overcome Resistance to BET Inhibitors
  Blood. Apr, 2020  |   Pubmed ID: 32068780
• Bempegaldesleukin Selectively Depletes Intratumoral Tregs and Potentiates T Cell-mediated Cancer Therapy
  Nature Communications. Jan, 2020  |   Pubmed ID: 32005826
• A Phase II Study of Cabozantinib and Androgen Ablation in Patients with Hormone-Naïve Metastatic Prostate Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 03, 2020  |   Pubmed ID: 31941830
• Hepatic Tumor Formation in Adult Mice Developmentally Exposed to Organotin
  Environmental Health Perspectives. Jan, 2020  |   Pubmed ID: 31939706
• Metabolic Dysregulation in the Wilson's Disease Mouse Model
  Proceedings of the National Academy of Sciences of the United States of America. 01, 2020  |   Pubmed ID: 31924743
• Long Noncoding RNA BHLHE40-AS1 Promotes Early Breast Cancer Progression Through Modulating IL-6/STAT3 Signaling
  Journal of Cellular Biochemistry. Jul, 2020  |   Pubmed ID: 31907974
• Critical Role of Cytosolic DNA and Its Sensing Adaptor STING in Aortic Degeneration, Dissection, and Rupture
  Circulation. Jan, 2020  |   Pubmed ID: 31887080
• RNA Sequencing-based Transcriptome Profiling of Cardiac Tissue Implicates Novel Putative Disease Mechanisms in FLNC-associated Arrhythmogenic Cardiomyopathy
  International Journal of Cardiology. Mar, 2020  |   Pubmed ID: 31843279
• The Testis-specific Serine Proteases PRSS44, PRSS46, and PRSS54 Are Dispensable for Male Mouse Fertility†
  Biology of Reproduction. 02, 2020  |   Pubmed ID: 31403672
• Epigenetic Loss of AOX1 Expression Via EZH2 Leads to Metabolic Deregulations and Promotes Bladder Cancer Progression
  Oncogene. Oct, 2020  |   Pubmed ID: 31383940
• Exercise Restores Dysregulated Gene Expression in a Mouse Model of Arrhythmogenic Cardiomyopathy
  Cardiovascular Research. May, 2020  |   Pubmed ID: 31350552
• Metabolomic Biomarkers Are Associated with Mortality in Patients with Cirrhosis Caused by Primary Biliary Cholangitis or Primary Sclerosing Cholangitis
  Future Science OA. Dec, 2019  |   Pubmed ID: 32025330
• MicroRNA-509-3p Inhibits Cellular Migration, Invasion, and Proliferation, and Sensitizes Osteosarcoma to Cisplatin
  Scientific Reports. Dec, 2019  |   Pubmed ID: 31836741
• Correction: Expression of Ganglioside GD2, Reprogram the Lipid Metabolism and EMT Phenotype in Bladder Cancer
  Oncotarget. Nov, 2019  |   Pubmed ID: 31827727
• DNA Methylation in AgRP Neurons Regulates Voluntary Exercise Behavior in Mice
  Nature Communications. Dec, 2019  |   Pubmed ID: 31792207
• Loss of the E2 SUMO-conjugating Enzyme in Oocytes During Ovarian Folliculogenesis Causes Infertility in Mice
  Development (Cambridge, England). Dec, 2019  |   Pubmed ID: 31704792
• Erratum to "Distinct Lipidomic Landscapes Associated with Clinical Stages of Urothelial Cancer of the Bladder" [Eur Urol Focus 2018;4:907-915]
  European Urology Focus. Sep, 2019  |   Pubmed ID: 31474581
• The Genomic Landscape of Estrogen Receptor α Binding Sites in Mouse Mammary Gland
  PloS One. 2019  |   Pubmed ID: 31408468
• Depletion of Endothelial Prolyl Hydroxylase Domain Protein 2 and 3 Promotes Cardiomyocyte Proliferation and Prevents Ventricular Failure Induced by Myocardial Infarction
  Circulation. Jul, 2019  |   Pubmed ID: 31356139
• DNA Methylation Patterns in Bladder Tumors of African American Patients Point to Distinct Alterations in Xenobiotic Metabolism
  Carcinogenesis. Nov, 2019  |   Pubmed ID: 31284295
• Short-term RANKL Exposure Initiates a Neoplastic Transcriptional Program in the Basal Epithelium of the Murine Salivary Gland
  Cytokine. Nov, 2019  |   Pubmed ID: 31226438
• Association Between Elevated Placental Polycyclic Aromatic Hydrocarbons (PAHs) and PAH-DNA Adducts from Superfund Sites in Harris County, and Increased Risk of Preterm Birth (PTB)
  Biochemical and Biophysical Research Communications. Aug, 2019  |   Pubmed ID: 31208719
• CRISPR/Cas9-mediated Genome Editing Reveals 30 Testis-enriched Genes Dispensable for Male Fertility in Mice†
  Biology of Reproduction. 08, 2019  |   Pubmed ID: 31201419
• Mitochondrial Pyruvate Import is a Metabolic Vulnerability in Androgen Receptor-driven Prostate Cancer
  Nature Metabolism. Jan, 2019  |   Pubmed ID: 31198906
• Oncogenic LncRNA Downregulates Cancer Cell Antigen Presentation and Intrinsic Tumor Suppression
  Nature Immunology. Jul, 2019  |   Pubmed ID: 31160797
• A Genomic Atlas of Systemic Interindividual Epigenetic Variation in Humans
  Genome Biology. Jun, 2019  |   Pubmed ID: 31155008
• Cigarette Smoke-induced Reduction of C1q Promotes Emphysema
  JCI Insight. 05, 2019  |   Pubmed ID: 31112138
• Transcriptomic Profiling Identifies Novel Mechanisms of Transcriptional Regulation of the Cytochrome P450 (Cyp)3a11 Gene
  Scientific Reports. Apr, 2019  |   Pubmed ID: 31040347
• RUNX1-targeted Therapy for AML Expressing Somatic or Germline Mutation in RUNX1
  Blood. 07, 2019  |   Pubmed ID: 31023702
• Activating P53 Family Member TAp63: A Novel Therapeutic Strategy for Targeting P53-altered Tumors
  Cancer. Jul, 2019  |   Pubmed ID: 31012964
• REST-DRD2 Mechanism Impacts Glioblastoma Stem Cell-mediated Tumorigenesis
  Neuro-oncology. Jun, 2019  |   Pubmed ID: 30953587
• Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2019  |   Pubmed ID: 30846479
• Tegavivint and the β-Catenin/ALDH Axis in Chemotherapy-Resistant and Metastatic Osteosarcoma
  Journal of the National Cancer Institute. Nov, 2019  |   Pubmed ID: 30793158
• Genomic Reorganization of Lamin-Associated Domains in Cardiac Myocytes Is Associated With Differential Gene Expression and DNA Methylation in Human Dilated Cardiomyopathy
  Circulation Research. Apr, 2019  |   Pubmed ID: 30739589
• A Prospective Targeted Serum Metabolomics Study of Pancreatic Cancer in Postmenopausal Women
  Cancer Prevention Research (Philadelphia, Pa.). Apr, 2019  |   Pubmed ID: 30723176
• DNA Damage Response/TP53 Pathway Is Activated and Contributes to the Pathogenesis of Dilated Cardiomyopathy Associated With LMNA (Lamin A/C) Mutations
  Circulation Research. Mar, 2019  |   Pubmed ID: 30696354
• Superior Efficacy of Cotreatment with BET Protein Inhibitor and BCL2 or MCL1 Inhibitor Against AML Blast Progenitor Cells
  Blood Cancer Journal. Jan, 2019  |   Pubmed ID: 30647404
• Bacteria-to-Human Protein Networks Reveal Origins of Endogenous DNA Damage
  Cell. Jan, 2019  |   Pubmed ID: 30633903
• Targeting Nuclear β-catenin As Therapy for Post-myeloproliferative Neoplasm Secondary AML
  Leukemia. 06, 2019  |   Pubmed ID: 30575820
• Correction To: The Emerging Roles of Steroid Hormone Receptors in Ductal Carcinoma in Situ (DCIS) of the Breast
  Journal of Mammary Gland Biology and Neoplasia. Mar, 2019  |   Pubmed ID: 30465315
• Beyond Autoantibodies: Biologic Roles of Human Autoreactive B Cells in Rheumatoid Arthritis Revealed by RNA-Sequencing
  Arthritis & Rheumatology (Hoboken, N.J.). Apr, 2019  |   Pubmed ID: 30407753
• MicroRNA-30a As a Candidate Underlying Sex-specific Differences in Neonatal Hyperoxic Lung Injury: Implications for BPD
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Jan, 2019  |   Pubmed ID: 30382766
• Inositol Polyphosphate 4-phosphatase Type II Regulation of Androgen Receptor Activity
  Oncogene. Feb, 2019  |   Pubmed ID: 30228349
• Plasma Urea Cycle Metabolites May Be Useful Biomarkers in Children With Eosinophilic Esophagitis
  Frontiers in Pediatrics. 2018  |   Pubmed ID: 30687688
• The Transcription Factor POU3F2 Regulates a Gene Coexpression Network in Brain Tissue from Patients with Psychiatric Disorders
  Science Translational Medicine. Dec, 2018  |   Pubmed ID: 30545964
• The Emerging Roles of Steroid Hormone Receptors in Ductal Carcinoma in Situ (DCIS) of the Breast
  Journal of Mammary Gland Biology and Neoplasia. Dec, 2018  |   Pubmed ID: 30338425
• TGF-β1 Programmed Myeloid-derived Suppressor Cells (MDSC) Acquire Immune-stimulating and Tumor Killing Activity Capable of Rejecting Established Tumors in Combination with Radiotherapy
  Oncoimmunology. 2018  |   Pubmed ID: 30288358
• Steroid Receptor Coactivator-2 Controls the Pentose Phosphate Pathway Through RPIA in Human Endometrial Cancer Cells
  Scientific Reports. Sep, 2018  |   Pubmed ID: 30177747
• Allele-specific Epigenome Maps Reveal Sequence-dependent Stochastic Switching at Regulatory Loci
  Science (New York, N.Y.). Sep, 2018  |   Pubmed ID: 30139913
• APOBEC Mutation Drives Early-onset Squamous Cell Carcinomas in Recessive Dystrophic Epidermolysis Bullosa
  Science Translational Medicine. Aug, 2018  |   Pubmed ID: 30135250
• Correction: MYCN Acts As a Direct Co-regulator of P53 in MYCN Amplified Neuroblastoma
  Oncotarget. Jul, 2018  |   Pubmed ID: 30042831
• Unbiased Lipidomic Profiling of Triple-Negative Breast Cancer Tissues Reveals the Association of Sphingomyelin Levels with Patient Disease-Free Survival
  Metabolites. Jul, 2018  |   Pubmed ID: 30011843
• MiR-30a Remodels Subcutaneous Adipose Tissue Inflammation to Improve Insulin Sensitivity in Obesity
  Diabetes. 12, 2018  |   Pubmed ID: 30002134
• Expression of Long Noncoding RNA Promotes Glycolysis in Breast Cancer
  Cancer Research. Aug, 2018  |   Pubmed ID: 29967256
• Mechanisms of Skeletal Muscle Wasting in a Mouse Model for Myotonic Dystrophy Type 1
  Human Molecular Genetics. Aug, 2018  |   Pubmed ID: 29771332
• MYCN Acts As a Direct Co-regulator of P53 in MYCN Amplified Neuroblastoma
  Oncotarget. Apr, 2018  |   Pubmed ID: 29755654
• Schistosomiasis Induces Persistent DNA Methylation and Tuberculosis-Specific Immune Changes
  Journal of Immunology (Baltimore, Md. : 1950). Jul, 2018  |   Pubmed ID: 29752313
• Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas
  Cell Reports. Apr, 2018  |   Pubmed ID: 29617660
• Metabolic Enzyme PFKFB4 Activates Transcriptional Coactivator SRC-3 to Drive Breast Cancer
  Nature. Apr, 2018  |   Pubmed ID: 29615789
• The NIEHS TaRGET II Consortium and Environmental Epigenomics
  Nature Biotechnology. Mar, 2018  |   Pubmed ID: 29509741
• An Integrative Transcriptomic Approach to Identify Depot Differences in Genes and MicroRNAs in Adipose Tissues from High Fat Fed Mice
  Oncotarget. Feb, 2018  |   Pubmed ID: 29507687
• GLUT12 Promotes Prostate Cancer Cell Growth and is Regulated by Androgens and CaMKK2 Signaling
  Endocrine-related Cancer. Apr, 2018  |   Pubmed ID: 29431615
• ICG-001 Exerts Potent Anticancer Activity Against Uveal Melanoma Cells
  Investigative Ophthalmology & Visual Science. Jan, 2018  |   Pubmed ID: 29332125
• Suppression of Activated FOXO Transcription Factors in the Heart Prolongs Survival in a Mouse Model of Laminopathies
  Circulation Research. Mar, 2018  |   Pubmed ID: 29317431
• Epigenetic Supersimilarity of Monozygotic Twin Pairs
  Genome Biology. Jan, 2018  |   Pubmed ID: 29310692
• Unique Metabolomic Signature Associated with Hepatorenal Dysfunction and Mortality in Cirrhosis
  Translational Research : the Journal of Laboratory and Clinical Medicine. May, 2018  |   Pubmed ID: 29291380
• Distinct TP63 Isoform-Driven Transcriptional Signatures Predict Tumor Progression and Clinical Outcomes
  Cancer Research. Jan, 2018  |   Pubmed ID: 29180475
• Distinct Lipidomic Landscapes Associated with Clinical Stages of Urothelial Cancer of the Bladder
  European Urology Focus. Dec, 2018  |   Pubmed ID: 28753886
• Expression of Ganglioside GD2, Reprogram the Lipid Metabolism and EMT Phenotype in Bladder Cancer
  Oncotarget. Nov, 2017  |   Pubmed ID: 29221154
• EWS-FLI1 and RNA Helicase A Interaction Inhibitor YK-4-279 Inhibits Growth of Neuroblastoma
  Oncotarget. Nov, 2017  |   Pubmed ID: 29212266
• Ronin Governs Early Heart Development by Controlling Core Gene Expression Programs
  Cell Reports. Nov, 2017  |   Pubmed ID: 29117561
• Systematic Analysis of Human Telomeric Dysfunction Using Inducible Telosome/shelterin CRISPR/Cas9 Knockout Cells
  Cell Discovery. 2017  |   Pubmed ID: 28955502
• Pharmacological Inhibition of CaMKK2 with the Selective Antagonist STO-609 Regresses NAFLD
  Scientific Reports. Sep, 2017  |   Pubmed ID: 28924233
• A New Mild Hyperthermia Device to Treat Vascular Involvement in Cancer Surgery
  Scientific Reports. Sep, 2017  |   Pubmed ID: 28900126
• Tead1 is Required for Maintaining Adult Cardiomyocyte Function, and Its Loss Results in Lethal Dilated Cardiomyopathy
  JCI Insight. Sep, 2017  |   Pubmed ID: 28878117
• Tobacco-Specific Carcinogens Induce Hypermethylation, DNA Adducts, and DNA Damage in Bladder Cancer
  Cancer Prevention Research (Philadelphia, Pa.). Oct, 2017  |   Pubmed ID: 28851690
• Sexual Dimorphism of the Pulmonary Transcriptome in Neonatal Hyperoxic Lung Injury: Identification of Angiogenesis As a Key Pathway
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Dec, 2017  |   Pubmed ID: 28818871
• MiR-130b Directly Targets ARHGAP1 to Drive Activation of a Metastatic CDC42-PAK1-AP1 Positive Feedback Loop in Ewing Sarcoma
  International Journal of Cancer. Nov, 2017  |   Pubmed ID: 28748534
• Peroxisomal Biogenesis is Genetically and Biochemically Linked to Carbohydrate Metabolism in Drosophila and Mouse
  PLoS Genetics. Jun, 2017  |   Pubmed ID: 28640802
• Vitamin D Receptor Activation Reduces VCaP Xenograft Tumor Growth and Counteracts ERG Activity Despite Induction of TMPRSS2:ERG
  Oncotarget. Jul, 2017  |   Pubmed ID: 28591703
• Glutamine Transporters Are Targets of Multiple Oncogenic Signaling Pathways in Prostate Cancer
  Molecular Cancer Research : MCR. Aug, 2017  |   Pubmed ID: 28507054
• Elevated TATA-binding Protein Expression Drives Vascular Endothelial Growth Factor Expression in Colon Cancer
  Oncotarget. Jul, 2017  |   Pubmed ID: 28415573
• SPOP Regulates Prostate Epithelial Cell Proliferation and Promotes Ubiquitination and Turnover of C-MYC Oncoprotein
  Oncogene. Aug, 2017  |   Pubmed ID: 28414305
• Role of Cytochrome P450 (CYP)1A in Hyperoxic Lung Injury: Analysis of the Transcriptome and Proteome
  Scientific Reports. Apr, 2017  |   Pubmed ID: 28377578
• Regulation of MiRNA-29c and Its Downstream Pathways in Preneoplastic Progression of Triple-negative Breast Cancer
  Oncotarget. Mar, 2017  |   Pubmed ID: 28160548
• Novel BET Protein Proteolysis-targeting Chimera Exerts Superior Lethal Activity Than Bromodomain Inhibitor (BETi) Against Post-myeloproliferative Neoplasm Secondary (s) AML Cells
  Leukemia. 09, 2017  |   Pubmed ID: 28042144
• REST Represses MiR-124 and MiR-203 to Regulate Distinct Oncogenic Properties of Glioblastoma Stem Cells
  Neuro-oncology. Apr, 2017  |   Pubmed ID: 28040710
• Transcriptional Regulation of Core Autophagy and Lysosomal Genes by the Androgen Receptor Promotes Prostate Cancer Progression
  Autophagy. Mar, 2017  |   Pubmed ID: 27977328
• Circadian Homeostasis of Liver Metabolism Suppresses Hepatocarcinogenesis
  Cancer Cell. Dec, 2016  |   Pubmed ID: 27889186