Janice M Leung UBC Centre for Heart Lung Innovation St. Paul’s Hospital Biography Publications Institution JoVE Articles Janice M Leung has not added a biography. If you are Janice M Leung and would like to personalize this page please email our Author Liaison for assistance. Publications Cluster Analysis to Identify Long COVID Phenotypes Using Xe Magnetic Resonance Imaging: A Multi-centre Evaluation The European Respiratory Journal. Feb, 2024 | Pubmed ID: 38331459 Single-cell RNA Sequencing of Bronchoscopy Specimens: Development of a Rapid Minimal Handling Protocol BioTechniques. Oct, 2023 | Pubmed ID: 37815826 Airway Epithelial-Derived Immune Mediators in COVID-19 Viruses. Jul, 2023 | Pubmed ID: 37631998 Predicting Steroid Responsiveness Using Airway Smooth Muscle in COPD: a HISTORIC Study The European Respiratory Journal. Jul, 2023 | Pubmed ID: 37474151 Methionine-producing Tumor Micro(be) Environment Fuels Growth of Solid Tumors Cellular Oncology (Dordrecht). Dec, 2023 | Pubmed ID: 37318751 Microbial Dysbiosis and the Host Airway Epithelial Response: Insights into HIV-associated COPD Using Multi'omics Profiling Respiratory Research. May, 2023 | Pubmed ID: 37143066 Characterization of the Lower Airways and Oral Microbiota in Healthy Young Persons in the Community Biomedicines. Mar, 2023 | Pubmed ID: 36979819 HIV and Chronic Lung Disease Current Opinion in HIV and AIDS. Mar, 2023 | Pubmed ID: 36722198 Systemic and Airway Epigenetic Disruptions Are Associated with Health Status in COPD Biomedicines. Jan, 2023 | Pubmed ID: 36672643 Common Respiratory Pathogens Other Than in Small Airways Are Associated With Neutrophilic Inflammation and Poor Health Status in Stable COPD Patients Chronic Obstructive Pulmonary Diseases (Miami, Fla.). Jan, 2023 | Pubmed ID: 36459695 Exposure to Diesel Exhaust Alters the Functional Metagenomic Composition of the Airway Microbiome in Former Smokers Environmental Research. Jan, 2023 | Pubmed ID: 36403657 The Blood DNA Methylation Clock GrimAge Is a Robust Surrogate for Airway Epithelia Aging Biomedicines. Dec, 2022 | Pubmed ID: 36551848 The Relationship Between the Epigenetic Aging Biomarker "grimage" and Lung Function in Both the Airway and Blood of People Living with HIV: An Observational Cohort Study EBioMedicine. Sep, 2022 | Pubmed ID: 35944348 Airway Eosinophilia on Bronchoalveolar Lavage and the Risk of Exacerbations in COPD Biomedicines. Jun, 2022 | Pubmed ID: 35740433 The Impact of IgG Subclass Deficiency on the Risk of Mortality in Hospitalized Patients with COPD Respiratory Research. May, 2022 | Pubmed ID: 35641962 Inhaled Corticosteroids Selectively Alter the Microbiome and Host Transcriptome in the Small Airways of Patients with Chronic Obstructive Pulmonary Disease Biomedicines. May, 2022 | Pubmed ID: 35625847 Pulmonary Function and Blood DNA Methylation: A Multiancestry Epigenome-Wide Association Meta-analysis American Journal of Respiratory and Critical Care Medicine. Aug, 2022 | Pubmed ID: 35536696 Airway Aging and Methylation Disruptions in HIV-associated Chronic Obstructive Pulmonary Disease American Journal of Respiratory and Critical Care Medicine. Jul, 2022 | Pubmed ID: 35426765 Distinct Bronchial Microbiome Precedes Clinical Diagnosis of Lung Cancer Molecular Cancer. Mar, 2022 | Pubmed ID: 35255902 Epigenetic Marker of Telomeric Age is Associated with Exacerbations and Hospitalizations in Chronic Obstructive Pulmonary Disease Respiratory Research. Dec, 2021 | Pubmed ID: 34937547 Epigenetic Blood Biomarkers of Ageing and Mortality in COPD The European Respiratory Journal. Dec, 2021 | Pubmed ID: 34561282 Effects of Inhaled Corticosteroid/Long-Acting β-Agonist Combination on the Airway Microbiome of Patients with Chronic Obstructive Pulmonary Disease: A Randomized Controlled Clinical Trial (DISARM) American Journal of Respiratory and Critical Care Medicine. Nov, 2021 | Pubmed ID: 34464242 IgG Levels and Mortality in Chronic Obstructive Pulmonary Disease American Journal of Respiratory and Critical Care Medicine. Aug, 2021 | Pubmed ID: 33945775 Macrophages with Reduced Expressions of Classical M1 and M2 Surface Markers in Human Bronchoalveolar Lavage Fluid Exhibit Pro-inflammatory Gene Signatures Scientific Reports. Apr, 2021 | Pubmed ID: 33859282 Inhaled Corticosteroids Downregulate SARS-CoV-2-related Genes in COPD: Results from a Randomised Controlled Trial The European Respiratory Journal. Jul, 2021 | Pubmed ID: 33795322 Olodaterol Exerts Anti-inflammatory Effects on COPD Airway Epithelial Cells Respiratory Research. Feb, 2021 | Pubmed ID: 33622325 DNA Methylation is Associated with Airflow Obstruction in Patients Living with HIV Thorax. May, 2021 | Pubmed ID: 33443234 Abundance of Non-Polarized Lung Macrophages with Poor Phagocytic Function in Chronic Obstructive Pulmonary Disease (COPD) Biomedicines. Oct, 2020 | Pubmed ID: 33050042 COVID-19 and COPD The European Respiratory Journal. Aug, 2020 | Pubmed ID: 32817205 Serum IgG Levels and Risk of COPD Hospitalization: A Pooled Meta-analysis Chest. Oct, 2020 | Pubmed ID: 32439504 Smoking, ACE-2 and COVID-19: Ongoing Controversies The European Respiratory Journal. Jul, 2020 | Pubmed ID: 32430431 Reply To: "Current Smoking is Not Associated with COVID-19" The European Respiratory Journal. Jun, 2020 | Pubmed ID: 32366490 COVID-19 and Nicotine As a Mediator of ACE-2 The European Respiratory Journal. Jun, 2020 | Pubmed ID: 32350104 ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19 The European Respiratory Journal. May, 2020 | Pubmed ID: 32269089 Effects of Sex and Chronic Cigarette Smoke Exposure on the Mouse Cecal Microbiome PloS One. 2020 | Pubmed ID: 32251484 The Safety and Efficacy of Marijuana in Persons Living with HIV AIDS Reviews. 2019 | Pubmed ID: 31332397 Introduction to Precision Medicine in COPD The European Respiratory Journal. Apr, 2019 | Pubmed ID: 30679189 Sputum Microbiome Is Associated with 1-Year Mortality After Chronic Obstructive Pulmonary Disease Hospitalizations American Journal of Respiratory and Critical Care Medicine. May, 2019 | Pubmed ID: 30376356 Inhaled Corticosteroids in COPD: the Final Verdict Is… The European Respiratory Journal. Dec, 2018 | Pubmed ID: 30545961 Decreased Microbiome Diversity in the HIV Small Airway Epithelium Respiratory Research. Jul, 2018 | Pubmed ID: 30053882 Relationship of Absolute Telomere Length With Quality of Life, Exacerbations, and Mortality in COPD Chest. Aug, 2018 | Pubmed ID: 30017346 Decreased Telomere Length in the Small Airway Epithelium Suggests Accelerated Aging in the Lungs of Persons Living with Human Immunodeficiency Virus (HIV) Respiratory Research. Jun, 2018 | Pubmed ID: 29895291 Serum IgG Subclass Levels and Risk of Exacerbations and Hospitalizations in Patients with COPD Respiratory Research. Feb, 2018 | Pubmed ID: 29444682 Asthma-COPD Overlap Syndrome: Pathogenesis, Clinical Features, and Therapeutic Targets BMJ (Clinical Research Ed.). Sep, 2017 | Pubmed ID: 28947632 Concern of Underdiagnosing Asthma-COPD Overlap Syndrome if Age Limit of 40 years for Asthma is Used The European Respiratory Journal. Aug, 2017 | Pubmed ID: 28775052 Responsiveness to Ipratropium Bromide in Male and Female Patients with Mild to Moderate Chronic Obstructive Pulmonary Disease EBioMedicine. May, 2017 | Pubmed ID: 28461224 Serum IgG and Risk of Exacerbations and Hospitalizations in Chronic Obstructive Pulmonary Disease The Journal of Allergy and Clinical Immunology. Oct, 2017 | Pubmed ID: 28456620 The Role of Acute and Chronic Respiratory Colonization and Infections in the Pathogenesis of COPD Respirology (Carlton, Vic.). May, 2017 | Pubmed ID: 28342288 Longitudinal Study of Surrogate Aging Measures During Human Immunodeficiency Virus Seroconversion Aging. Feb, 2017 | Pubmed ID: 28237978 Emphysema Distribution and Diffusion Capacity Predict Emphysema Progression in Human Immunodeficiency Virus Infection PloS One. 2016 | Pubmed ID: 27902753 The Bronchial Epithelial Cell Bacterial Microbiome and Host Response in Patients Infected with Human Immunodeficiency Virus BMC Pulmonary Medicine. Nov, 2016 | Pubmed ID: 27829448 COPD Exacerbation Biomarkers Validated Using Multiple Reaction Monitoring Mass Spectrometry PloS One. 2016 | Pubmed ID: 27525416 A Systematic Review of Diagnostic Biomarkers of COPD Exacerbation PloS One. 2016 | Pubmed ID: 27434033 Airway Hyperresponsiveness in Chronic Obstructive Pulmonary Disease: A marker of Asthma-chronic Obstructive Pulmonary Disease Overlap Syndrome? The Journal of Allergy and Clinical Immunology. Dec, 2016 | Pubmed ID: 27345171 What is Asthma-COPD Overlap Syndrome? Towards a Consensus Definition from a Round Table Discussion The European Respiratory Journal. Sep, 2016 | Pubmed ID: 27338195 Chronic Obstructive Pulmonary Disease and Stroke. Strange Bedfellows American Journal of Respiratory and Critical Care Medicine. Feb, 2016 | Pubmed ID: 26829416 Empowering Family Physicians to Impart Proper Inhaler Teaching to Patients with Chronic Obstructive Pulmonary Disease and Asthma Canadian Respiratory Journal. 2015 | Pubmed ID: 26436910 Absolute Leukocyte Telomere Length in HIV-infected and Uninfected Individuals: Evidence of Accelerated Cell Senescence in HIV-associated Chronic Obstructive Pulmonary Disease PloS One. 2015 | Pubmed ID: 25885433 Plasma Pro-surfactant Protein B and Lung Function Decline in Smokers The European Respiratory Journal. Apr, 2015 | Pubmed ID: 25614175 COPD Exacerbations: Reducing the Burden by Predicting the Future? The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease. Dec, 2014 | Pubmed ID: 25517799 A Sum Greater Than Its Parts The European Respiratory Journal. Dec, 2014 | Pubmed ID: 25435523 Smoke and Mirrors: the Perils of Water-pipe Smoking and Implications for Western Countries Chest. Oct, 2014 | Pubmed ID: 25287994 COPD in Never Smokers: Prognosis Unveiled The Lancet. Respiratory Medicine. Sep, 2013 | Pubmed ID: 24461602 Biomarkers in Airway Diseases Canadian Respiratory Journal. 2013 | Pubmed ID: 23762888 Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function Rachel L Eddy1,2, George H Xu3, Jonathon A Leipsic1,4, Janice M Leung1,2, Don D Sin1,2, Chase S Hall5, Roger C Tam3,4 1UBC Centre for Heart Lung Innovation, St. Paul’s Hospital, 2Division of Respiratory Medicine, Department of Medicine, University of British Columbia, 3School of Biomedical Engineering, University of British Columbia, 4Department of Radiology, University of British Columbia, 5Division of Pulmonary and Critical Care Medicine, University of Kansas Medical Center JoVE 66257 Medicina
Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function Rachel L Eddy1,2, George H Xu3, Jonathon A Leipsic1,4, Janice M Leung1,2, Don D Sin1,2, Chase S Hall5, Roger C Tam3,4 1UBC Centre for Heart Lung Innovation, St. Paul’s Hospital, 2Division of Respiratory Medicine, Department of Medicine, University of British Columbia, 3School of Biomedical Engineering, University of British Columbia, 4Department of Radiology, University of British Columbia, 5Division of Pulmonary and Critical Care Medicine, University of Kansas Medical Center JoVE 66257 Medicina