Rolf Müller

Publications

• Drug Administration Routes Impact the Metabolism of a Synthetic Cannabinoid in the Zebrafish Larvae Model
  Molecules (Basel, Switzerland). Sep, 2020  |   Pubmed ID: 33003405
• Amidochelocardin Overcomes Resistance Mechanisms Exerted on Tetracyclines and Natural Chelocardin
  Antibiotics (Basel, Switzerland). Sep, 2020  |   Pubmed ID: 32962088
• Natural Products Impacting DNA Methyltransferases and Histone Deacetylases
  Frontiers in Pharmacology. 2020  |   Pubmed ID: 32903500
• How to Study the Metabolism of New Psychoactive Substances for the Purpose of Toxicological Screenings-A Follow-Up Study Comparing Pooled Human Liver S9, HepaRG Cells, and Zebrafish Larvae
  Frontiers in Chemistry. 2020  |   Pubmed ID: 32766204
• Erratum for Wallenstein Et Al., "ClbR Is the Key Transcriptional Activator of Colibactin Gene Expression in Escherichia Coli"
  MSphere. Jul, 2020  |   Pubmed ID: 32727866
• ClbR Is the Key Transcriptional Activator of Colibactin Gene Expression in Escherichia Coli
  MSphere. 07, 2020  |   Pubmed ID: 32669458
• Biosynthesis of Cittilins, Unusual Ribosomally Synthesized and Post-translationally Modified Peptides from
  ACS Chemical Biology. 08, 2020  |   Pubmed ID: 32639716
• Human Microbial Metabolite Mimicry As a Strategy to Expand the Chemical Space of Potential Drugs
  Drug Discovery Today. Sep, 2020  |   Pubmed ID: 32562605
• Dual-Seq Reveals Genome and Transcriptome of Caedibacter Taeniospiralis, Obligate Endosymbiont of Paramecium
  Scientific Reports. 06, 2020  |   Pubmed ID: 32546745
• 2-Hydroxysorangiadenosine: Structure and Biosynthesis of a Myxobacterial Sesquiterpene-Nucleoside
  Molecules (Basel, Switzerland). Jun, 2020  |   Pubmed ID: 32527018
• -Aryl-3-mercaptosuccinimides As Antivirulence Agents Targeting Elastase and Collagenases
  Journal of Medicinal Chemistry. Aug, 2020  |   Pubmed ID: 32470298
• Thioholgamide A, a New Anti-Proliferative Anti-Tumor Agent, Modulates Macrophage Polarization and Metabolism
  Cancers. May, 2020  |   Pubmed ID: 32438733
• Protein-Templated Hit Identification Through an Ugi Four-Component Reaction
  Chemistry (Weinheim an Der Bergstrasse, Germany). May, 2020  |   Pubmed ID: 32428268
• Targeting Cellular Fatty Acid Synthesis Limits T Helper and Innate Lymphoid Cell Function During Intestinal Inflammation and Infection
  Mucosal Immunology. Apr, 2020  |   Pubmed ID: 32355319
• Toxicokinetics and Toxicodynamics of the Fentanyl Homologs Cyclopropanoyl-1-benzyl-4´-fluoro-4-anilinopiperidine and Furanoyl-1-benzyl-4-anilinopiperidine
  Archives of Toxicology. 06, 2020  |   Pubmed ID: 32249346
• Squalenyl Hydrogen Sulfate Nanoparticles for Simultaneous Delivery of Tobramycin and an Alkylquinolone Quorum Sensing Inhibitor Enable the Eradication of P. aeruginosa Biofilm Infections
  Angewandte Chemie (International Ed. in English). 06, 2020  |   Pubmed ID: 32243047
• The ROK Like Protein of Myxococcus Xanthus DK1622 Acts As a Pleiotropic Transcriptional Regulator for Secondary Metabolism
  Journal of Biotechnology. Mar, 2020  |   Pubmed ID: 32057784
• The Glucocorticoid-induced Leucine Zipper Mediates Statin-induced Muscle Damage
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2020  |   Pubmed ID: 32030813
• Cystobactamid 507: Concise Synthesis, Mode of Action, and Optimization Toward More Potent Antibiotics
  Chemistry (Weinheim an Der Bergstrasse, Germany). Jun, 2020  |   Pubmed ID: 31984562
• Characterization of Bromelain Indicates a Molar Excess of Inhibitor Vs. Enzyme Molecules, a Jacalin-like Lectin and Maillard Reaction Products
  Journal of Pharmaceutical and Biomedical Analysis. Mar, 2020  |   Pubmed ID: 31951942
• Myxobacteria-Derived Outer Membrane Vesicles: Potential Applicability Against Intracellular Infections
  Cells. 01, 2020  |   Pubmed ID: 31940898
• Structures of Lipoprotein Signal Peptidase II from Staphylococcus Aureus Complexed with Antibiotics Globomycin and Myxovirescin
  Nature Communications. 01, 2020  |   Pubmed ID: 31919415
• Semisynthesis and Biological Evaluation of Amidochelocardin Derivatives As Broad-spectrum Antibiotics
  European Journal of Medicinal Chemistry. Feb, 2020  |   Pubmed ID: 31911294
• Dual-function Chromogenic Screening-based CRISPR/Cas9 Genome Editing System for Actinomycetes
  Applied Microbiology and Biotechnology. Jan, 2020  |   Pubmed ID: 31788711
• PLGA Nanocapsules Improve the Delivery of Clarithromycin to Kill Intracellular Staphylococcus Aureus and Mycobacterium Abscessus
  Nanomedicine : Nanotechnology, Biology, and Medicine. 02, 2020  |   Pubmed ID: 31751769
• In Depth Natural Product Discovery - Myxobacterial Strains That Provided Multiple Secondary Metabolites
  Biotechnology Advances. Mar - Apr, 2020  |   Pubmed ID: 31707075
• The Cytotoxic Natural Product Vioprolide A Targets Nucleolar Protein 14, Which Is Essential for Ribosome Biogenesis
  Angewandte Chemie (International Ed. in English). 01, 2020  |   Pubmed ID: 31658409
• Chemical Synthesis of Tripeptide Thioesters for the Biotechnological Incorporation into the Myxobacterial Secondary Metabolite Argyrin Via Mutasynthesis
  Beilstein Journal of Organic Chemistry. 2019  |   Pubmed ID: 31839838
• Homologous Bd Oxidases Share the Same Architecture but Differ in Mechanism
  Nature Communications. 11, 2019  |   Pubmed ID: 31723136
• The MRNA-binding Protein TTP/ZFP36 in Hepatocarcinogenesis and Hepatocellular Carcinoma
  Cancers. Nov, 2019  |   Pubmed ID: 31717307
• Production of a Dibrominated Aromatic Secondary Metabolite by a Planctomycete Implies Complex Interaction with a Macroalgal Host
  ACS Chemical Biology. 12, 2019  |   Pubmed ID: 31644258
• Differential Regulation of AMP-activated Protein Kinase in Healthy and Cancer Cells Explains Why V-ATPase Inhibition Selectively Kills Cancer Cells
  The Journal of Biological Chemistry. 11, 2019  |   Pubmed ID: 31604821
• Polyunsaturated Fatty Acid Production by Yarrowia Lipolytica Employing Designed Myxobacterial PUFA Synthases
  Nature Communications. 09, 2019  |   Pubmed ID: 31492836
• Watching DNA Replication Inhibitors in Action: Exploiting Time-Lapse Microfluidic Microscopy As a Tool for Target-Drug Interaction Studies in
  Antimicrobial Agents and Chemotherapy. 10, 2019  |   Pubmed ID: 31383667
• Connecting Lysosomes and Mitochondria - a Novel Role for Lipid Metabolism in Cancer Cell Death
  Cell Communication and Signaling : CCS. 07, 2019  |   Pubmed ID: 31358011
• Production Optimization and Biosynthesis Revision of Corallopyronin A, a Potent Anti-filarial Antibiotic
  Metabolic Engineering. 09, 2019  |   Pubmed ID: 31340171
• Chivosazole A Modulates Protein-Protein Interactions of Actin
  Journal of Natural Products. 07, 2019  |   Pubmed ID: 31260301
• ACC1 (Acetyl Coenzyme A Carboxylase 1) Is a Potential Immune Modulatory Target of Cerebral Ischemic Stroke
  Stroke. 07, 2019  |   Pubmed ID: 31177975
• Integrating Culture-based Antibiotic Resistance Profiles with Whole-genome Sequencing Data for 11,087 Clinical Isolates
  Genomics, Proteomics & Bioinformatics. 04, 2019  |   Pubmed ID: 31100356
• A High-affinity Fluorescence Probe for Copper(II) Ions and Its Application in Fluorescence Lifetime Correlation Spectroscopy
  Analytical and Bioanalytical Chemistry. Jun, 2019  |   Pubmed ID: 31025181
• Synthesis of New Cyclomarin Derivatives and Their Biological Evaluation Towards Mycobacterium Tuberculosis and Plasmodium Falciparum
  Chemistry (Weinheim an Der Bergstrasse, Germany). Jul, 2019  |   Pubmed ID: 31012978
• Targeting Actin Inhibits Repair of Doxorubicin-induced DNA Damage: a Novel Therapeutic Approach for Combination Therapy
  Cell Death & Disease. 04, 2019  |   Pubmed ID: 30944311
• A Highly Polymorphic Receptor Governs Many Distinct Self-Recognition Types Within the Order
  MBio. 02, 2019  |   Pubmed ID: 30755513
• Engineering Atypical Tetracycline Formation in Amycolatopsis Sulphurea for the Production of Modified Chelocardin Antibiotics
  ACS Chemical Biology. 03, 2019  |   Pubmed ID: 30747520
• Dedication: Heinz Floss and Christopher Walsh-pioneers in Natural Product Chemical Biology
  Journal of Industrial Microbiology & Biotechnology. Mar, 2019  |   Pubmed ID: 30729342
• Introduction to the Special Issue: "Natural Product Discovery and Development in the Genomic Era: 2019"
  Journal of Industrial Microbiology & Biotechnology. Mar, 2019  |   Pubmed ID: 30729341
• Tools for Studying the Metabolism of New Psychoactive Substances for Toxicological Screening Purposes - A Comparative Study Using Pooled Human Liver S9, HepaRG Cells, and Zebrafish Larvae
  Toxicology Letters. May, 2019  |   Pubmed ID: 30682400
• Aurantimycin Resistance Genes Contribute to Survival of Listeria Monocytogenes During Life in the Environment
  Molecular Microbiology. 04, 2019  |   Pubmed ID: 30648305
• Armeniaspirol Antibiotic Biosynthesis: Chlorination and Oxidative Dechlorination Steps Affording Spiro[4.4]non-8-ene
  Chembiochem : a European Journal of Chemical Biology. 03, 2019  |   Pubmed ID: 30556942
• Novel Methoxymethacrylate Natural Products Uncovered by Statistics-Based Mining of the Myxococcus Fulvus Secondary Metabolome
  ACS Chemical Biology. 01, 2019  |   Pubmed ID: 30543288
• Class I Methyltransferase VioH Catalyzes Unusual S-Adenosyl-l-methionine Cyclization Leading to 4-Methylazetidinecarboxylic Acid Formation During Vioprolide Biosynthesis
  ACS Chemical Biology. 01, 2019  |   Pubmed ID: 30540188
• Corrigendum to Biocompatible Bacteria-derived Vesicles Show Inherent Antimicrobial Activity [Journal of Controlled Release, Volume 290, Page 46-55 (2018), Page 46-55]
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Jan, 2019  |   Pubmed ID: 30529880
• Genome Mining Reveals Uncommon Alkylpyrones As Type III PKS Products from Myxobacteria
  Journal of Industrial Microbiology & Biotechnology. Mar, 2019  |   Pubmed ID: 30506464
• Expressing Cytotoxic Compounds in Escherichia Coli Nissle 1917 for Tumor-targeting Therapy
  Research in Microbiology. Mar, 2019  |   Pubmed ID: 30447257
• -Acylated Amino Acid Methyl Esters from Marine Group Bacteria
  Beilstein Journal of Organic Chemistry. 2018  |   Pubmed ID: 30591820
• Aspherical and Spherical InvA497-Functionalized Nanocarriers for Intracellular Delivery of Anti-Infective Agents
  Pharmaceutical Research. Dec, 2018  |   Pubmed ID: 30519925
• BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1β Maturation in Macrophages
  Cell Reports. 11, 2018  |   Pubmed ID: 30485805
• Adaptation of a Bacterial Multidrug Resistance System Revealed by the Structure and Function of AlbA
  Journal of the American Chemical Society. 12, 2018  |   Pubmed ID: 30422653
• Synthetic Biology Approaches and Combinatorial Biosynthesis Towards Heterologous Lipopeptide Production
  Chemical Science. Oct, 2018  |   Pubmed ID: 30319751
• Biocompatible Bacteria-derived Vesicles Show Inherent Antimicrobial Activity
  Journal of Controlled Release : Official Journal of the Controlled Release Society. 11, 2018  |   Pubmed ID: 30292423
• Characterization of an Unusual Glycerate Esterification Process in Vioprolide Biosynthesis
  ACS Chemical Biology. 11, 2018  |   Pubmed ID: 30286293
• A Polyphasic Approach Leads to Seven New Species of the Cellulose-decomposing Genus Sorangium, Sorangium Ambruticinum Sp. Nov., Sorangium Arenae Sp. Nov., Sorangium Bulgaricum Sp. Nov., Sorangium Dawidii Sp. Nov., Sorangium Kenyense Sp. Nov., Sorangium Orientale Sp. Nov. and Sorangium Reichenbachii Sp. Nov
  International Journal of Systematic and Evolutionary Microbiology. Nov, 2018  |   Pubmed ID: 30234476
• The Vacuolar-type ATPase Inhibitor Archazolid Increases Tumor Cell Adhesion to Endothelial Cells by Accumulating Extracellular Collagen
  PloS One. 2018  |   Pubmed ID: 30204757
• The Translational Machinery of Human CD4 T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling
  Cell Metabolism. 12, 2018  |   Pubmed ID: 30197303
• Metabolic and Biosynthetic Diversity in Marine Myxobacteria
  Marine Drugs. Sep, 2018  |   Pubmed ID: 30189599
• Activation of the NLRP3 Inflammasome by Hyaboron, a New Asymmetric Boron-Containing Macrodiolide from the Myxobacterium Hyalangium Minutum
  ACS Chemical Biology. 10, 2018  |   Pubmed ID: 30183250
• Future Directions of Marine Myxobacterial Natural Product Discovery Inferred from Metagenomics
  Marine Drugs. Aug, 2018  |   Pubmed ID: 30158489
• Simulacricoccus Ruber Gen. Nov., Sp. Nov., a Microaerotolerant, Non-fruiting, Myxospore-forming Soil Myxobacterium and Emended Description of the Family Myxococcaceae
  International Journal of Systematic and Evolutionary Microbiology. Oct, 2018  |   Pubmed ID: 30113300
• Iterative Methylations Resulting in the Biosynthesis of the T-Butyl Group Catalyzed by a B-Dependent Radical SAM Enzyme in Cystobactamid Biosynthesis
  Methods in Enzymology. 2018  |   Pubmed ID: 30097093
• Structure, Total Synthesis, and Biosynthesis of Chloromyxamides: Myxobacterial Tetrapeptides Featuring an Uncommon 6-Chloromethyl-5-methoxypipecolic Acid Building Block
  Angewandte Chemie (International Ed. in English). 10, 2018  |   Pubmed ID: 30088846
• Self-resistance Guided Genome Mining Uncovers New Topoisomerase Inhibitors from Myxobacteria
  Chemical Science. Jun, 2018  |   Pubmed ID: 29910943
• A Fluorescence Anisotropy Assay to Discover and Characterize Ligands Targeting the Maytansine site of Tubulin
  Nature Communications. 05, 2018  |   Pubmed ID: 29844393
• Concepts and Methods to Access Novel Antibiotics from Actinomycetes
  Antibiotics (Basel, Switzerland). May, 2018  |   Pubmed ID: 29789481
• The Alkylquinolone Repertoire of Pseudomonas Aeruginosa is Linked to Structural Flexibility of the FabH-like 2-Heptyl-3-hydroxy-4(1H)-quinolone (PQS) Biosynthesis Enzyme PqsBC
  Chembiochem : a European Journal of Chemical Biology. Jul, 2018  |   Pubmed ID: 29722462
• Biosynthesis and Heterologous Production of Vioprolides: Rational Biosynthetic Engineering and Unprecedented 4-Methylazetidinecarboxylic Acid Formation
  Angewandte Chemie (International Ed. in English). 07, 2018  |   Pubmed ID: 29694699
• Octapeptins: Lipopeptide Antibiotics Against Multidrug-Resistant Superbugs
  Cell Chemical Biology. 04, 2018  |   Pubmed ID: 29677485
• Two Types of Threonine-Tagged Lipopeptides Synergize in Host Colonization by Pathogenic Burkholderia Species
  ACS Chemical Biology. 05, 2018  |   Pubmed ID: 29669203
• Discovery of Recombinases Enables Genome Mining of Cryptic Biosynthetic Gene Clusters in Burkholderiales Species
  Proceedings of the National Academy of Sciences of the United States of America. 05, 2018  |   Pubmed ID: 29666226
• Genome-wide Mutant Profiling Predicts the Mechanism of a Lipid II Binding Antibiotic
  Nature Chemical Biology. Apr, 2018  |   Pubmed ID: 29662210
• Improved Riboflavin Production with Ashbya Gossypii from Vegetable Oil Based on C Metabolic Network Analysis with Combined Labeling Analysis by GC/MS, LC/MS, 1D, and 2D NMR
  Metabolic Engineering. 05, 2018  |   Pubmed ID: 29654833
• Correlating Chemical Diversity with Taxonomic Distance for Discovery of Natural Products in Myxobacteria
  Nature Communications. 02, 2018  |   Pubmed ID: 29476047
• Nannocystis Konarekensis Sp. Nov., a Novel Myxobacterium from an Iranian Desert
  International Journal of Systematic and Evolutionary Microbiology. Mar, 2018  |   Pubmed ID: 29458458
• Production of Extracellular Heterologous Proteins in Streptomyces Rimosus, Producer of the Antibiotic Oxytetracycline
  Applied Microbiology and Biotechnology. Mar, 2018  |   Pubmed ID: 29417200
• Biosynthesis of the Klebsiella Oxytoca Pathogenicity Factor Tilivalline: Heterologous Expression, in Vitro Biosynthesis, and Inhibitor Development
  ACS Chemical Biology. 03, 2018  |   Pubmed ID: 29389112
• Draft Genome Sequence and Annotation of the Obligate Bacterial Endosymbiont , Causative Agent of the Killer Phenotype in
  Genome Announcements. Jan, 2018  |   Pubmed ID: 29348333
• ExoCET: Exonuclease in Vitro Assembly Combined with RecET Recombination for Highly Efficient Direct DNA Cloning from Complex Genomes
  Nucleic Acids Research. 03, 2018  |   Pubmed ID: 29272442
• A "Motif-Oriented" Total Synthesis of Nannocystin Ax. Preparation and Biological Assessment of Analogues
  The Journal of Organic Chemistry. 07, 2018  |   Pubmed ID: 29265814
• Oxygenated N-Acyl Alanine Methyl Esters (NAMEs) from the Marine Bacterium Roseovarius Tolerans EL-164
  Journal of Natural Products. 01, 2018  |   Pubmed ID: 29261310
• ExoCET: Exonuclease in Vitro Assembly Combined with RecET Recombination for Highly Efficient Direct DNA Cloning from Complex Genomes
  Nucleic Acids Research. 03, 2018  |   Pubmed ID: 29240926
• Crocadepsins-Depsipeptides from the Myxobacterium Chondromyces Crocatus Found by a Genome Mining Approach
  ACS Chemical Biology. 01, 2018  |   Pubmed ID: 29220569
• Acetyl-CoA Carboxylase 1 Regulates Endothelial Cell Migration by Shifting the Phospholipid Composition
  Journal of Lipid Research. 02, 2018  |   Pubmed ID: 29208696
• Homospermidine Lipids: A Compound Class Specifically Formed During Fruiting Body Formation of Myxococcus Xanthus DK1622
  ACS Chemical Biology. 01, 2018  |   Pubmed ID: 29185703
• Targeting De Novo Lipogenesis As a Novel Approach in Anti-cancer Therapy
  British Journal of Cancer. 01, 2018  |   Pubmed ID: 29112683
• Biosynthesis of Methyl-proline Containing Griselimycins, Natural Products with Anti-tuberculosis Activity
  Chemical Science. Nov, 2017  |   Pubmed ID: 29163906
• The Natural Product Carolacton Inhibits Folate-dependent C1 Metabolism by Targeting FolD/MTHFD
  Nature Communications. 11, 2017  |   Pubmed ID: 29142318
• Heterologous Production of Myxobacterial α-pyrone Antibiotics in Myxococcus Xanthus
  Metabolic Engineering. 11, 2017  |   Pubmed ID: 29030273
• The Biofilm Inhibitor Carolacton Enters Gram-Negative Cells: Studies Using a TolC-Deficient Strain of
  MSphere. Sep-Oct, 2017  |   Pubmed ID: 28959742
• Synthetic Biology Approaches to Establish a Heterologous Production System for Coronatines
  Metabolic Engineering. 11, 2017  |   Pubmed ID: 28951265
• Biosynthesis and Total Synthesis of Pyrronazol B: a Secondary Metabolite from Nannocystis Pusilla
  Chemistry (Weinheim an Der Bergstrasse, Germany). Nov, 2017  |   Pubmed ID: 28944573
• Linoleic and Palmitoleic Acid Block Streptokinase-mediated Plasminogen Activation and Reduce Severity of Invasive Group A Streptococcal Infection
  Scientific Reports. 09, 2017  |   Pubmed ID: 28924140
• CYP17A1-independent Production of the Neurosteroid-derived 5α-pregnan-3β,6α-diol-20-one in Androgen-responsive Prostate Cancer Cell Lines Under Serum Starvation and Inhibition by Abiraterone
  The Journal of Steroid Biochemistry and Molecular Biology. 11, 2017  |   Pubmed ID: 28890368
• Total Biosynthesis of the Pyrrolo[4,2]benzodiazepine Scaffold Tomaymycin on an In Vitro Reconstituted NRPS System
  Cell Chemical Biology. Oct, 2017  |   Pubmed ID: 28890318
• Optimization of the Biotechnological Production of a Novel Class of Anti-MRSA Antibiotics from Chitinophaga Sancti
  Microbial Cell Factories. Aug, 2017  |   Pubmed ID: 28818083
• Total Synthesis of Crocagin A
  Angewandte Chemie (International Ed. in English). 10, 2017  |   Pubmed ID: 28812331
• Inhibition of the V-ATPase by Archazolid A: A New Strategy to Inhibit EMT
  Molecular Cancer Therapeutics. 11, 2017  |   Pubmed ID: 28775146
• Total Syntheses of Cystobactamids and Structural Confirmation of Cystobactamid 919-2
  Angewandte Chemie (International Ed. in English). 10, 2017  |   Pubmed ID: 28731542
• Pyxipyrrolones: Structure Elucidation and Biosynthesis of Cytotoxic Myxobacterial Metabolites
  Angewandte Chemie (International Ed. in English). 08, 2017  |   Pubmed ID: 28590072
• Structure and Biosynthesis of Crocagins: Polycyclic Posttranslationally Modified Ribosomal Peptides from Chondromyces Crocatus
  Angewandte Chemie (International Ed. in English). 06, 2017  |   Pubmed ID: 28544148
• AibA/AibB Induces an Intramolecular Decarboxylation in Isovalerate Biosynthesis by Myxococcus Xanthus
  Angewandte Chemie (International Ed. in English). 08, 2017  |   Pubmed ID: 28508504
• Heterologous Production and Yield Improvement of Epothilones in Burkholderiales Strain DSM 7029
  ACS Chemical Biology. 07, 2017  |   Pubmed ID: 28467833
• Novel and Revisited Approaches in Antituberculosis Drug Discovery
  Current Opinion in Biotechnology. 12, 2017  |   Pubmed ID: 28427007
• Long-Chain Alkyl Cyanides: Unprecedented Volatile Compounds Released by Pseudomonas and Micromonospora Bacteria
  Angewandte Chemie (International Ed. in English). 04, 2017  |   Pubmed ID: 28276609
• Selective Upregulation of TNFα Expression in Classically-activated Human Monocyte-derived Macrophages (M1) Through Pharmacological Interference with V-ATPase
  Biochemical Pharmacology. 04, 2017  |   Pubmed ID: 28189727
• Vitiosangium Cumulatum Gen. Nov., Sp. Nov. and Vitiosangium Subalbum Sp. Nov., Soil Myxobacteria, and Emended Descriptions of the Genera Archangium and Angiococcus, and of the Family Cystobacteraceae
  International Journal of Systematic and Evolutionary Microbiology. May, 2017  |   Pubmed ID: 28141508
• Modulation of Actin Dynamics As Potential Macrophage Subtype-targeting Anti-tumour Strategy
  Scientific Reports. 01, 2017  |   Pubmed ID: 28134280
• Solving the Puzzle of One-Carbon Loss in Ripostatin Biosynthesis
  Angewandte Chemie (International Ed. in English). 02, 2017  |   Pubmed ID: 28098952
• Disorazoles Block Group A Streptococcal Invasion into Epithelial Cells Via Interference with the Host Factor Ezrin
  Cell Chemical Biology. Feb, 2017  |   Pubmed ID: 28089757
• Biosynthesis of Branched Alkoxy Groups: Iterative Methyl Group Alkylation by a Cobalamin-Dependent Radical SAM Enzyme
  Journal of the American Chemical Society. 02, 2017  |   Pubmed ID: 28040895
• V-ATPase Inhibition Increases Cancer Cell Stiffness and Blocks Membrane Related Ras Signaling - a New Option for HCC Therapy
  Oncotarget. Feb, 2017  |   Pubmed ID: 28036299
• The AibR-isovaleryl Coenzyme A Regulator and Its DNA Binding Site - a Model for the Regulation of Alternative De Novo Isovaleryl Coenzyme A Biosynthesis in Myxococcus Xanthus
  Nucleic Acids Research. 02, 2017  |   Pubmed ID: 27940564
• Racemicystis Persica Sp. Nov., a Myxobacterium from Soil
  International Journal of Systematic and Evolutionary Microbiology. Feb, 2017  |   Pubmed ID: 27902273
• Heterologous Expression of the Plant Cysteine Protease Bromelain and Its Inhibitor in Pichia Pastoris
  Biotechnology Progress. 01, 2017  |   Pubmed ID: 27860461
• Inactivation of SACE_3446, a TetR Family Transcriptional Regulator, Stimulates Erythromycin Production in
  Synthetic and Systems Biotechnology. Mar, 2016  |   Pubmed ID: 29062926
• Interrogation of for Efficient Production of Avermectins
  Synthetic and Systems Biotechnology. Mar, 2016  |   Pubmed ID: 29062922
• Strategies for the Discovery and Development of New Antibiotics from Natural Products: Three Case Studies
  Current Topics in Microbiology and Immunology. 2016  |   Pubmed ID: 27738913
• Structure and Substrate Recognition of the Bottromycin Maturation Enzyme BotP
  Chembiochem : a European Journal of Chemical Biology. 12, 2016  |   Pubmed ID: 27653442
• Corrigendum: Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation
  Frontiers in Physiology. 2016  |   Pubmed ID: 27489546
• Crystal Structure of AibC, a Reductase Involved in Alternative De Novo Isovaleryl Coenzyme A Biosynthesis in Myxococcus Xanthus
  Acta Crystallographica. Section F, Structural Biology Communications. 08, 2016  |   Pubmed ID: 27487931
• The Biofilm Inhibitor Carolacton Inhibits Planktonic Growth of Virulent Pneumococci Via a Conserved Target
  Scientific Reports. 07, 2016  |   Pubmed ID: 27404808
• Isolation, Structure Elucidation, and (Bio)Synthesis of Haprolid, a Cell-Type-Specific Myxobacterial Cytotoxin
  Angewandte Chemie (International Ed. in English). 08, 2016  |   Pubmed ID: 27404448
• Predicting the Presence of Uncommon Elements in Unknown Biomolecules from Isotope Patterns
  Analytical Chemistry. 08, 2016  |   Pubmed ID: 27398867
• The Structure of LiuC, a 3-Hydroxy-3-Methylglutaconyl CoA Dehydratase Involved in Isovaleryl-CoA Biosynthesis in Myxococcus Xanthus, Reveals Insights into Specificity and Catalysis
  Chembiochem : a European Journal of Chemical Biology. 09, 2016  |   Pubmed ID: 27271456
• RecET Direct Cloning and Redαβ Recombineering of Biosynthetic Gene Clusters, Large Operons or Single Genes for Heterologous Expression
  Nature Protocols. 07, 2016  |   Pubmed ID: 27254463
• Discovery of the First Small-molecule CsrA-RNA Interaction Inhibitors Using Biophysical Screening Technologies
  Future Medicinal Chemistry. 06, 2016  |   Pubmed ID: 27253623
• Isolation, Structure Elucidation, Biosynthesis, and Synthesis of Antalid, a Secondary Metabolite from Polyangium Species
  Organic Letters. 06, 2016  |   Pubmed ID: 27220069
• Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation
  Frontiers in Physiology. 2016  |   Pubmed ID: 27199763
• Structure-function Analysis for the Hydroxylation of Δ4 C21-steroids by the Myxobacterial CYP260B1
  FEBS Letters. 06, 2016  |   Pubmed ID: 27177597
• Susceptibility of Different Mouse Wild Type Strains to Develop Diet-Induced NAFLD/AFLD-Associated Liver Disease
  PloS One. 2016  |   Pubmed ID: 27167736
• MDM2 Antagonist Nutlin-3a Sensitizes Tumors to V-ATPase Inhibition
  Molecular Oncology. 08, 2016  |   Pubmed ID: 27157929
• Crystal Structure of the HMG-CoA Synthase MvaS from the Gram-Negative Bacterium Myxococcus Xanthus
  Chembiochem : a European Journal of Chemical Biology. 07, 2016  |   Pubmed ID: 27124816
• Room Temperature Electrocompetent Bacterial Cells Improve DNA Transformation and Recombineering Efficiency
  Scientific Reports. Apr, 2016  |   Pubmed ID: 27095488
• Racemicystis Crocea Gen. Nov., Sp. Nov., a Soil Myxobacterium in the Family Polyangiaceae
  International Journal of Systematic and Evolutionary Microbiology. Jun, 2016  |   Pubmed ID: 27046779
• Overproduction of Magnetosomes by Genomic Amplification of Biosynthesis-Related Gene Clusters in a Magnetotactic Bacterium
  Applied and Environmental Microbiology. 05, 2016  |   Pubmed ID: 26969709
• Genetic Engineering and Heterologous Expression of the Disorazol Biosynthetic Gene Cluster Via Red/ET Recombineering
  Scientific Reports. Feb, 2016  |   Pubmed ID: 26875499
• Effects of Halide Ions on the Carbamidocyclophane Biosynthesis in Nostoc Sp. CAVN2
  Marine Drugs. Jan, 2016  |   Pubmed ID: 26805858
• Investigations to the Antibacterial Mechanism of Action of Kendomycin
  PloS One. 2016  |   Pubmed ID: 26795276
• Genome Analysis of the Fruiting Body-Forming Myxobacterium Chondromyces Crocatus Reveals High Potential for Natural Product Biosynthesis
  Applied and Environmental Microbiology. Jan, 2016  |   Pubmed ID: 26773087
• Cylindrofridins A-C, Linear Cylindrocyclophane-Related Alkylresorcinols from the Cyanobacterium Cylindrospermum Stagnale
  Journal of Natural Products. Jan, 2016  |   Pubmed ID: 26684177
• The Mechanism of Action of Lysobactin
  Journal of the American Chemical Society. Jan, 2016  |   Pubmed ID: 26683668
• Gen. Nov., Sp. Nov. and Sp. Nov., Novel Myxobacteria with Promising Biotechnological Applications
  International Journal of Systematic and Evolutionary Microbiology. Feb, 2016  |   Pubmed ID: 26637815
• Metabolic Engineering of Pseudomonas Putida for Production of Docosahexaenoic Acid Based on a Myxobacterial PUFA Synthase
  Metabolic Engineering. Jan, 2016  |   Pubmed ID: 26617065
• Mutations Improving Production and Secretion of Extracellular Lipase by Burkholderia Glumae PG1
  Applied Microbiology and Biotechnology. Feb, 2016  |   Pubmed ID: 26476653
• Structural Insights into Anthranilate Priming During Type II Polyketide Biosynthesis
  ACS Chemical Biology. Jan, 2016  |   Pubmed ID: 26473393
• Two More Pieces of the Colibactin Genotoxin Puzzle from Show Incorporation of an Unusual 1-aminocyclopropanecarboxylic Acid Moiety
  Chemical Science. May, 2015  |   Pubmed ID: 28706687
• Soraphen A: A Probe for Investigating the Role of De Novo Lipogenesis During Viral Infection
  ACS Infectious Diseases. Mar, 2015  |   Pubmed ID: 27622463
• Anti-leukemic Effects of the V-ATPase Inhibitor Archazolid A
  Oncotarget. Dec, 2015  |   Pubmed ID: 26496038
• Direct Cloning and Heterologous Expression of the Salinomycin Biosynthetic Gene Cluster from Streptomyces Albus DSM41398 in Streptomyces Coelicolor A3(2)
  Scientific Reports. Oct, 2015  |   Pubmed ID: 26459865
• Two of a Kind--The Biosynthetic Pathways of Chlorotonil and Anthracimycin
  ACS Chemical Biology. Nov, 2015  |   Pubmed ID: 26348978
• Rickenyls A-E, Antioxidative Terphenyls from the Fungus Hypoxylon Rickii (Xylariaceae, Ascomycota)
  Phytochemistry. Oct, 2015  |   Pubmed ID: 26296745
• Minimum Information About a Biosynthetic Gene Cluster
  Nature Chemical Biology. Sep, 2015  |   Pubmed ID: 26284661
• Cystochromones, Unusual Chromone-Containing Polyketides from the Myxobacterium Cystobacter Sp. MCy9104
  Journal of Natural Products. Aug, 2015  |   Pubmed ID: 26214047
• Macyranones: Structure, Biosynthesis, and Binding Mode of an Unprecedented Epoxyketone That Targets the 20S Proteasome
  Journal of the American Chemical Society. Jul, 2015  |   Pubmed ID: 26050527
• Antibiotics. Targeting DnaN for Tuberculosis Therapy Using Novel Griselimycins
  Science (New York, N.Y.). Jun, 2015  |   Pubmed ID: 26045430
• Biosynthetic Studies of Telomycin Reveal New Lipopeptides with Enhanced Activity
  Journal of the American Chemical Society. Jun, 2015  |   Pubmed ID: 26043159
• AntiSMASH 3.0-a Comprehensive Resource for the Genome Mining of Biosynthetic Gene Clusters
  Nucleic Acids Research. Jul, 2015  |   Pubmed ID: 25948579
• Advanced Mutasynthesis Studies on the Natural α-pyrone Antibiotic Myxopyronin from Myxococcus Fulvus
  Chembiochem : a European Journal of Chemical Biology. Apr, 2015  |   Pubmed ID: 25757034
• Total Syntheses and Biological Evaluation of Miuraenamides
  Angewandte Chemie (International Ed. in English). Apr, 2015  |   Pubmed ID: 25688545
• Rational and Efficient Site-directed Mutagenesis of Adenylation Domain Alters Relative Yields of Luminmide Derivatives in Vivo
  Biotechnology and Bioengineering. Jul, 2015  |   Pubmed ID: 25683597
• A New Recombineering System for Photorhabdus and Xenorhabdus
  Nucleic Acids Research. Mar, 2015  |   Pubmed ID: 25539914
• Heterologous Expression of an Orphan NRPS Gene Cluster from Paenibacillus Larvae in Escherichia Coli Revealed Production of Sevadicin
  Journal of Biotechnology. Jan, 2015  |   Pubmed ID: 25529345
• Anti-MRSA-acting Carbamidocyclophanes H-L from the Vietnamese Cyanobacterium Nostoc Sp. CAVN2
  The Journal of Antibiotics. Mar, 2015  |   Pubmed ID: 25182484
• Aggregicoccus Edonensis Gen. Nov., Sp. Nov., an Unusually Aggregating Myxobacterium Isolated from a Soil Sample
  International Journal of Systematic and Evolutionary Microbiology. Mar, 2015  |   Pubmed ID: 24591423
• Elevated Free Cholesterol in a P62 Overexpression Model of Non-alcoholic Steatohepatitis
  World Journal of Gastroenterology. Dec, 2014  |   Pubmed ID: 25548482
• De Novo Fatty Acid Synthesis Controls the Fate Between Regulatory T and T Helper 17 Cells
  Nature Medicine. Nov, 2014  |   Pubmed ID: 25282359
• Improving Natural Products Identification Through Targeted LC-MS/MS in an Untargeted Secondary Metabolomics Workflow
  Analytical Chemistry. Nov, 2014  |   Pubmed ID: 25280058
• In Vitro and in Vivo Characterization of the Actin Polymerizing Compound Chondramide As an Angiogenic Inhibitor
  Cardiovascular Research. Nov, 2014  |   Pubmed ID: 25239826
• Heterologous Production of Glidobactins/luminmycins in Escherichia Coli Nissle Containing the Glidobactin Biosynthetic Gene Cluster from Burkholderia DSM7029
  Chembiochem : a European Journal of Chemical Biology. Oct, 2014  |   Pubmed ID: 25147087
• Minicystis Rosea Gen. Nov., Sp. Nov., a Polyunsaturated Fatty Acid-rich and Steroid-producing Soil Myxobacterium
  International Journal of Systematic and Evolutionary Microbiology. Nov, 2014  |   Pubmed ID: 25114157
• Antimalarial Activity of the Myxobacterial Macrolide Chlorotonil A
  Antimicrobial Agents and Chemotherapy. Nov, 2014  |   Pubmed ID: 25114138
• Targeting V-ATPase in Primary Human Monocytes by Archazolid Potently Represses the Classical Secretion of Cytokines Due to Accumulation at the Endoplasmic Reticulum
  Biochemical Pharmacology. Oct, 2014  |   Pubmed ID: 25107704
• A Highly Unusual Polyketide Synthase Directs Dawenol Polyene Biosynthesis in Stigmatella Aurantiaca
  Journal of Biotechnology. Dec, 2014  |   Pubmed ID: 25102237
• Hyalachelins A-C, Unusual Siderophores Isolated from the Terrestrial Myxobacterium Hyalangium Minutum
  Organic Letters. Aug, 2014  |   Pubmed ID: 25058569
• Interactions of the Natural Product Kendomycin and the 20S Proteasome
  Journal of Molecular Biology. Sep, 2014  |   Pubmed ID: 25038530
• Biosynthesis of Crocacin Involves an Unusual Hydrolytic Release Domain Showing Similarity to Condensation Domains
  Chemistry & Biology. Jul, 2014  |   Pubmed ID: 24981773
• Secondary Metabolomics: the Impact of Mass Spectrometry-based Approaches on the Discovery and Characterization of Microbial Natural Products
  Natural Product Reports. Jun, 2014  |   Pubmed ID: 24763662
• Cystomanamides: Structure and Biosynthetic Pathway of a Family of Glycosylated Lipopeptides from Myxobacteria
  Organic Letters. May, 2014  |   Pubmed ID: 24735013
• Biosynthesis of Magnetic Nanostructures in a Foreign Organism by Transfer of Bacterial Magnetosome Gene Clusters
  Nature Nanotechnology. Mar, 2014  |   Pubmed ID: 24561353
• V-ATPase Inhibition Regulates Anoikis Resistance and Metastasis of Cancer Cells
  Molecular Cancer Therapeutics. Apr, 2014  |   Pubmed ID: 24482380
• Oleamycins A and B: New Antibacterial Cyclic Hexadepsipeptides Isolated from a Terrestrial Streptomyces Sp
  The Journal of Antibiotics. Apr, 2014  |   Pubmed ID: 24448627
• Improved Seamless Mutagenesis by Recombineering Using CcdB for Counterselection
  Nucleic Acids Research. Mar, 2014  |   Pubmed ID: 24369425
• V-ATPase Inhibition Overcomes Trastuzumab Resistance In breast Cancer
  Molecular Oncology. Feb, 2014  |   Pubmed ID: 24055142
• Modular Construction of a Functional Artificial Epothilone Polyketide Pathway
  ACS Synthetic Biology. Oct, 2014  |   Pubmed ID: 23654254
• Jahnellamides, α-keto-β-methionine-containing Peptides from the Terrestrial Myxobacterium Jahnella Sp.: Structure and Biosynthesis
  Organic Letters. Nov, 2013  |   Pubmed ID: 24199909
• Concerted Action of P450 Plus Helper Protein to Form the Amino-hydroxy-piperidone Moiety of the Potent Protease Inhibitor Crocapeptin
  Journal of the American Chemical Society. Nov, 2013  |   Pubmed ID: 24171398
• Microsclerodermins from Terrestrial Myxobacteria: an Intriguing Biosynthesis Likely Connected to a Sponge Symbiont
  Journal of the American Chemical Society. Nov, 2013  |   Pubmed ID: 24124771
• Combining in Silico and Biophysical Methods for the Development of Pseudomonas Aeruginosa Quorum Sensing Inhibitors: an Alternative Approach for Structure-based Drug Design
  Journal of Medicinal Chemistry. Nov, 2013  |   Pubmed ID: 24083807
• Exploring Chemical Diversity of α-pyrone Antibiotics: Molecular Basis of Myxopyronin Biosynthesis
  Chembiochem : a European Journal of Chemical Biology. Sep, 2013  |   Pubmed ID: 23983106
• Discovery and Biological Activity of New Chondramides from Chondromyces Sp
  Chembiochem : a European Journal of Chemical Biology. Sep, 2013  |   Pubmed ID: 23959765
• Synthesis and Biological Activities of the Respiratory Chain Inhibitor Aurachin D and New Ring Versus Chain Analogues
  Beilstein Journal of Organic Chemistry. 2013  |   Pubmed ID: 23946854
• Oleaceran: a Novel Spiro[isobenzofuran-1,2'-naptho[1,8-bc]furan] Isolated from a Terrestrial Streptomyces Sp
  Organic Letters. Jul, 2013  |   Pubmed ID: 23802119
• High-titer Heterologous Production in E. Coli of Lyngbyatoxin, a Protein Kinase C Activator from an Uncultured Marine Cyanobacterium
  ACS Chemical Biology. Sep, 2013  |   Pubmed ID: 23751865
• In Vivo Evidence for a Prodrug Activation Mechanism During Colibactin Maturation
  Chembiochem : a European Journal of Chemical Biology. Jul, 2013  |   Pubmed ID: 23744512
• Lorneic Acids C and D, New Trialkyl-substituted Aromatic Acids Isolated from a Terrestrial Streptomyces Sp
  The Journal of Antibiotics. Jun, 2013  |   Pubmed ID: 23549352
• Enhancer Binding Proteins Act As Hetero-oligomers and Link Secondary Metabolite Production to Myxococcal Development, Motility, and Predation
  Chemistry & Biology. Nov, 2012  |   Pubmed ID: 23177199
• 种合成和 Post-translationally 修改肽天然产物： 概述和建议的一套通用的命名法。
  Natural Product Reports. Nov, 2012  |   Pubmed ID: 23165928
• The Interplay of Lung Surfactant Proteins and Lipids Assimilates the Macrophage Clearance of Nanoparticles
  PloS One. 2012  |   Pubmed ID: 22802970
• Pretubulysin: from Hypothetical Biosynthetic Intermediate to Potential Lead in Tumor Therapy
  PloS One. 2012  |   Pubmed ID: 22616003
• Methods to Optimize Myxobacterial Fermentations Using Off-gas Analysis
  Microbial Cell Factories. May, 2012  |   Pubmed ID: 22571441
• Myxobacterium-produced Antibiotic TA (myxovirescin) Inhibits Type II Signal Peptidase
  Antimicrobial Agents and Chemotherapy. Apr, 2012  |   Pubmed ID: 22232277
• Molluscicidal Metabolites from an Assemblage of Palmyra Atoll Cyanobacteria
  Journal of Natural Products. May, 2011  |   Pubmed ID: 21473610
• Fatty Acid-related Phylogeny of Myxobacteria As an Approach to Discover Polyunsaturated Omega-3/6 Fatty Acids
  Journal of Bacteriology. Apr, 2011  |   Pubmed ID: 21317327
• Insights into an Unusual Nonribosomal Peptide Synthetase Biosynthesis: Identification and Characterization of the GE81112 Biosynthetic Gene Cluster
  The Journal of Biological Chemistry. Oct, 2010  |   Pubmed ID: 20710026
• Characterization of a Novel Type of Oxidative Decarboxylase Involved in the Biosynthesis of the Styryl Moiety of Chondrochloren from an Acylated Tyrosine
  The Journal of Biological Chemistry. Apr, 2010  |   Pubmed ID: 20080978
• Genome Mining in Sorangium Cellulosum So Ce56: Identification and Characterization of the Homologous Electron Transfer Proteins of a Myxobacterial Cytochrome P450
  The Journal of Biological Chemistry. Oct, 2009  |   Pubmed ID: 19696019
• Efficient Transfer of Two Large Secondary Metabolite Pathway Gene Clusters into Heterologous Hosts by Transposition
  Nucleic Acids Research. Oct, 2008  |   Pubmed ID: 18701643
• GeneTrail--advanced Gene Set Enrichment Analysis
  Nucleic Acids Research. Jul, 2007  |   Pubmed ID: 17526521
• The Unique DKxanthene Secondary Metabolite Family from the Myxobacterium Myxococcus Xanthus is Required for Developmental Sporulation
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2006  |   Pubmed ID: 17148609
• Biosynthetic Pathway of Pseudomonas Aeruginosa 4-hydroxy-2-alkylquinolines
  Journal of Bacteriology. Jun, 2005  |   Pubmed ID: 15901684