Shuei-Liong Lin Department of Integrated Diagnostics & Therapeutics National Taiwan University Hospital Biography Publications Institution JoVE Articles Shuei-Liong Lin has not added a biography. If you are Shuei-Liong Lin and would like to personalize this page please email our Author Liaison for assistance. Publications Effects of Medium Cut-Off Polyarylethersulfone and Polyvinylpyrrolidone Blend Membrane Dialyzers in Hemodialysis Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Membranes. Apr, 2022 | Pubmed ID: 35629769 Oxidative Stress-Induced Alterations of Cellular Localization and Expression of Aquaporin 1 Lead to Defected Water Transport Upon Peritoneal Fibrosis Biomedicines. Mar, 2022 | Pubmed ID: 35453560 Delivery of Sorafenib by Myofibroblast-targeted Nanoparticles for the Treatment of Renal Fibrosis Journal of Controlled Release : Official Journal of the Controlled Release Society. Apr, 2022 | Pubmed ID: 35429575 Exploring the Kidney Disease Data of Taiwan, a Country with the Highest Incidence and Prevalence of Treated ESKD Worldwide - Hints for Public Health and Policy Initiative Journal of the Formosan Medical Association = Taiwan Yi Zhi. 02, 2022 | Pubmed ID: 35216767 Targeting ER Protein TXNDC5 in Hepatic Stellate Cell Mitigates Liver Fibrosis by Repressing Non-canonical TGFβ Signalling Gut. Dec, 2021 | Pubmed ID: 34933915 Transforming Growth Factor-β1 Decreases Erythropoietin Production Through Repressing Hypoxia-inducible Factor 2α in Erythropoietin-producing Cells Journal of Biomedical Science. Nov, 2021 | Pubmed ID: 34724959 Characteristics of a Novel K416_F418delinsN Mutation in a Classical Aldosterone-Producing Adenoma Cancers. Sep, 2021 | Pubmed ID: 34572956 Alternative Complement Pathway Is Activated and Associated with Galactose-Deficient IgA Antibody in IgA Nephropathy Patients Frontiers in Immunology. 2021 | Pubmed ID: 34177889 Angiotensin II Receptor Blockers but Not Angiotensin-Converting Enzyme Inhibitors Are Associated With a Reduced Risk of Acute Kidney Injury After Major Surgery Frontiers in Pharmacology. 2021 | Pubmed ID: 33967804 FGF23 Ameliorates Ischemia-reperfusion Induced Acute Kidney Injury Via Modulation of Endothelial Progenitor Cells: Targeting SDF-1/CXCR4 Signaling Cell Death & Disease. 04, 2021 | Pubmed ID: 33866326 The Impact of Baseline Glomerular Filtration Rate on Subsequent Changes of Glomerular Filtration Rate in Patients with Chronic Kidney Disease Scientific Reports. 04, 2021 | Pubmed ID: 33846427 Kidney Pericyte Hypoxia-inducible Factor Regulates Erythropoiesis but Not Kidney Fibrosis Kidney International. 06, 2021 | Pubmed ID: 33812664 Outcomes of Coronavirus 2019 Infection in Patients with Chronic Kidney Disease: a Systematic Review and Meta-analysis Therapeutic Advances in Chronic Disease. 2021 | Pubmed ID: 33796245 Endoplasmic Reticulum Protein TXNDC5 Promotes Renal Fibrosis by Enforcing TGF-β Signaling in Kidney Fibroblasts The Journal of Clinical Investigation. 03, 2021 | Pubmed ID: 33465051 Targeting Fibroblast CD248 Attenuates CCL17-expressing Macrophages and Tissue Fibrosis Scientific Reports. 10, 2020 | Pubmed ID: 33033277 Fibroblast-enriched Endoplasmic Reticulum Protein TXNDC5 Promotes Pulmonary Fibrosis by Augmenting TGFβ Signaling Through TGFBR1 Stabilization Nature Communications. 08, 2020 | Pubmed ID: 32848143 Methylation in Pericytes After Acute Injury Promotes Chronic Kidney Disease The Journal of Clinical Investigation. 09, 2020 | Pubmed ID: 32749240 Hypochlorite-induced Porcine Model of Peritoneal Fibrosis Through the Activation of IL1β-CX3CL1-TGFβ1 Signal Axis Scientific Reports. 07, 2020 | Pubmed ID: 32661265 Effects and Safety of Statin and Ezetimibe Combination Therapy in Patients with Chronic Kidney Disease: A Systematic Review and Meta-Analysis Clinical Pharmacology and Therapeutics. 10, 2020 | Pubmed ID: 32320058 Integrating the Surprise Question, Palliative Care Screening Tool, and Clinical Risk Models to Identify Peritoneal Dialysis Patients With High One-Year Mortality Journal of Pain and Symptom Management. 09, 2020 | Pubmed ID: 32278098 Inflammatory Macrophages Switch to CCL17-expressing Phenotype and Promote Peritoneal Fibrosis The Journal of Pathology. 01, 2020 | Pubmed ID: 31579932 Rejuvenation: Turning Back the Clock of Aging Kidney Journal of the Formosan Medical Association = Taiwan Yi Zhi. May, 2020 | Pubmed ID: 31202499 Associations Between Preoperative Continuation of Renin-angiotensin System Inhibitor and Cardiac Surgery-associated Acute Kidney Injury: a Propensity Score-matching Analysis Journal of Nephrology. Dec, 2019 | Pubmed ID: 31595420 Angiopoietin 1 Influences Ischemic Reperfusion Renal Injury Via Modulating Endothelium Survival and Regeneration Molecular Medicine (Cambridge, Mass.). 02, 2019 | Pubmed ID: 30760202 Emergency Department Utilization and Resuscitation Rate Among Patients Receiving Maintenance Hemodialysis Journal of the Formosan Medical Association = Taiwan Yi Zhi. Dec, 2019 | Pubmed ID: 30711255 Erythropoietin Modulates Macrophages but Not Post-ischemic Acute Kidney Injury in Mice Journal of the Formosan Medical Association = Taiwan Yi Zhi. Jan, 2019 | Pubmed ID: 30414800 Heart Rate Variability As a Predictor of Rapid Renal Function Deterioration in Chronic Kidney Disease Patients Nephrology (Carlton, Vic.). Aug, 2019 | Pubmed ID: 30328166 Potential Target-organ Protection of Mineralocorticoid Receptor Antagonist in Acute Kidney Disease Journal of Hypertension. 01, 2019 | Pubmed ID: 30063639 Short- and Long-term Outcomes After Postsurgical Acute Kidney Injury Requiring Dialysis Clinical Epidemiology. 2018 | Pubmed ID: 30464638 Role of Renin-angiotensin System in Acute Kidney Injury-chronic Kidney Disease Transition Nephrology (Carlton, Vic.). Oct, 2018 | Pubmed ID: 30298669 Effects of Statin Use in Advanced Chronic Kidney Disease Patients Journal of Clinical Medicine. Sep, 2018 | Pubmed ID: 30227675 New-Onset Diabetes After Acute Kidney Injury Requiring Dialysis Diabetes Care. 10, 2018 | Pubmed ID: 30104297 Physiology and Pathophysiology of Renal Erythropoietin-producing Cells Journal of the Formosan Medical Association = Taiwan Yi Zhi. Nov, 2018 | Pubmed ID: 29655605 Endoplasmic Reticulum Protein TXNDC5 Augments Myocardial Fibrosis by Facilitating Extracellular Matrix Protein Folding and Redox-Sensitive Cardiac Fibroblast Activation Circulation Research. 04, 2018 | Pubmed ID: 29535165 Therapeutic Efficacy of Pentoxifylline on Proteinuria and Renal Progression: an Update Journal of Biomedical Science. Nov, 2017 | Pubmed ID: 29132351 Renin-Angiotensin System Inhibitor is Associated with Lower Risk of Ensuing Chronic Kidney Disease After Functional Recovery from Acute Kidney Injury Scientific Reports. 04, 2017 | Pubmed ID: 28406186 Restricted Use of Erythropoiesis-Stimulating Agent is Safe and Associated with Deferred Dialysis Initiation in Stage 5 Chronic Kidney Disease Scientific Reports. 03, 2017 | Pubmed ID: 28272424 Losartan Reduces Ensuing Chronic Kidney Disease and Mortality After Acute Kidney Injury Scientific Reports. Sep, 2016 | Pubmed ID: 27677327 Downregulation of Angiotensin Type 1 Receptor and Nuclear Factor-κB by Sirtuin 1 Contributes to Renoprotection in Unilateral Ureteral Obstruction Scientific Reports. Sep, 2016 | Pubmed ID: 27659793 A Low-salt Diet Increases the Expression of Renal Sirtuin 1 Through Activation of the Ghrelin Receptor in Rats Scientific Reports. 09, 2016 | Pubmed ID: 27600292 DNA Methyltransferase Inhibition Restores Erythropoietin Production in Fibrotic Murine Kidneys The Journal of Clinical Investigation. Feb, 2016 | Pubmed ID: 26731474 Enthusiasm for Induced Pluripotent Stem Cell-based Therapies in Kidney Regeneration Journal of the Formosan Medical Association = Taiwan Yi Zhi. 08, 2016 | Pubmed ID: 25043507 Circadian CLOCK Mediates Activation of Transforming Growth Factor-β Signaling and Renal Fibrosis Through Cyclooxygenase 2 The American Journal of Pathology. Dec, 2015 | Pubmed ID: 26458764 Prevalence and Clinical Correlates of Somatic Mutation in Aldosterone Producing Adenoma-Taiwanese Population Scientific Reports. Jun, 2015 | Pubmed ID: 26066391 Pentoxifylline Attenuates Proteinuria in Anti-Thy1 Glomerulonephritis Via Downregulation of Nuclear Factor-κB and Smad2/3 Signaling Molecular Medicine (Cambridge, Mass.). Apr, 2015 | Pubmed ID: 25879629 Multidisciplinary Care Program for Advanced Chronic Kidney Disease: Reduces Renal Replacement and Medical Costs The American Journal of Medicine. Jan, 2015 | Pubmed ID: 25149427 Blockade of Cysteine-rich Protein 61 Attenuates Renal Inflammation and Fibrosis After Ischemic Kidney Injury American Journal of Physiology. Renal Physiology. Sep, 2014 | Pubmed ID: 24920753 Lineage Tracing Reveals Distinctive Fates for Mesothelial Cells and Submesothelial Fibroblasts During Peritoneal Injury Journal of the American Society of Nephrology : JASN. Dec, 2014 | Pubmed ID: 24854266 Angiopoietin-2-induced Arterial Stiffness in CKD Journal of the American Society of Nephrology : JASN. Jun, 2014 | Pubmed ID: 24511140 Long-term Risk of Coronary Events After AKI Journal of the American Society of Nephrology : JASN. Mar, 2014 | Pubmed ID: 24503241 Microvascular Pericytes in Healthy and Diseased Kidneys International Journal of Nephrology and Renovascular Disease. Jan, 2014 | Pubmed ID: 24465134 Stem Cells and Kidney Regeneration Journal of the Formosan Medical Association = Taiwan Yi Zhi. Apr, 2014 | Pubmed ID: 24434243 Hemojuvelin Modulates Iron Stress During Acute Kidney Injury: Improved by Furin Inhibitor Antioxidants & Redox Signaling. Mar, 2014 | Pubmed ID: 23901875 Reply to Comment On: Is the Renoprotective Effect of Erythropoietin in Chronic Kidney Disease a Myth? Journal of the Formosan Medical Association = Taiwan Yi Zhi. Jan, 2014 | Pubmed ID: 23867578 Angiopoietins Modulate Endothelial Adaptation, Glomerular and Podocyte Hypertrophy After Uninephrectomy PloS One. 2013 | Pubmed ID: 24367525 The Role of Hypoxia-inducible Factors in Renal Fibrosis Journal of the Formosan Medical Association = Taiwan Yi Zhi. Oct, 2013 | Pubmed ID: 24120150 Association of the Variations in the HSD3β Gene with Primary Aldosteronism Journal of Hypertension. Jul, 2013 | Pubmed ID: 24006038 TLR-2/TLR-4 TREM-1 Signaling Pathway is Dispensable in Inflammatory Myeloid Cells During Sterile Kidney Injury PloS One. 2013 | Pubmed ID: 23844229 Decrease in Irisin in Patients with Chronic Kidney Disease PloS One. 2013 | Pubmed ID: 23667695 The Role of Angiopoietin-2 in Progressive Renal Fibrosis Journal of the Formosan Medical Association = Taiwan Yi Zhi. Apr, 2013 | Pubmed ID: 23537862 More is Not Better: Fluid Therapy in Critically Ill Patients with Acute Kidney Injury Journal of the Formosan Medical Association = Taiwan Yi Zhi. Mar, 2013 | Pubmed ID: 23473522 Angiopoietin-2 is Associated with Albuminuria and Microinflammation in Chronic Kidney Disease PloS One. 2013 | Pubmed ID: 23469160 Cysteine-rich Protein 61 Plays a Proinflammatory Role in Obstructive Kidney Fibrosis PloS One. 2013 | Pubmed ID: 23457573 LRP-6 is a Coreceptor for Multiple Fibrogenic Signaling Pathways in Pericytes and Myofibroblasts That Are Inhibited by DKK-1 Proceedings of the National Academy of Sciences of the United States of America. Jan, 2013 | Pubmed ID: 23302695 Novel Insights into Pericyte-myofibroblast Transition and Therapeutic Targets in Renal Fibrosis Journal of the Formosan Medical Association = Taiwan Yi Zhi. Nov, 2012 | Pubmed ID: 23217594 U-curve Association Between Timing of Renal Replacement Therapy Initiation and In-hospital Mortality in Postoperative Acute Kidney Injury PloS One. 2012 | Pubmed ID: 22952623 Clinical Outcomes and Predictors for ESRD and Mortality in Primary GN Clinical Journal of the American Society of Nephrology : CJASN. Sep, 2012 | Pubmed ID: 22798538 Advanced Age Affects the Outcome-predictive Power of RIFLE Classification in Geriatric Patients with Acute Kidney Injury Kidney International. Oct, 2012 | Pubmed ID: 22763817 The Role Played by Perivascular Cells in Kidney Interstitial Injury Clinical Nephrology. May, 2012 | Pubmed ID: 22551886 Pericyte TIMP3 and ADAMTS1 Modulate Vascular Stability After Kidney Injury Journal of the American Society of Nephrology : JASN. May, 2012 | Pubmed ID: 22383695 Safety Issues of Long-term Glucose Load in Patients on Peritoneal Dialysis--a 7-year Cohort Study PloS One. 2012 | Pubmed ID: 22303440 Acute-on-chronic Kidney Injury at Hospital Discharge is Associated with Long-term Dialysis and Mortality Kidney International. Dec, 2011 | Pubmed ID: 21832983 Primary Aldosteronism: Changes in Cystatin C-based Kidney Filtration, Proteinuria, and Renal Duplex Indices with Treatment Journal of Hypertension. Sep, 2011 | Pubmed ID: 21738054 Platelet-derived Growth Factor Receptor Signaling Activates Pericyte-myofibroblast Transition in Obstructive and Post-ischemic Kidney Fibrosis Kidney International. Dec, 2011 | Pubmed ID: 21716259 Impact of Timing of Renal Replacement Therapy Initiation on Outcome of Septic Acute Kidney Injury Critical Care (London, England). 2011 | Pubmed ID: 21645350 Café-au-lait Ascites in Encapsulating Peritoneal Sclerosis Kidney International. Jun, 2011 | Pubmed ID: 21566642 Kidney Impairment in Primary Aldosteronism Clinica Chimica Acta; International Journal of Clinical Chemistry. Jul, 2011 | Pubmed ID: 21345337 Targeting Endothelium-pericyte Cross Talk by Inhibiting VEGF Receptor Signaling Attenuates Kidney Microvascular Rarefaction and Fibrosis The American Journal of Pathology. Feb, 2011 | Pubmed ID: 21281822 Preoperative Proteinuria Predicts Adverse Renal Outcomes After Coronary Artery Bypass Grafting Journal of the American Society of Nephrology : JASN. Jan, 2011 | Pubmed ID: 21115618 Patients Supported by Extracorporeal Membrane Oxygenation and Acute Dialysis: Acute Physiology and Chronic Health Evaluation Score in Predicting Hospital Mortality Artificial Organs. Oct, 2010 | Pubmed ID: 21038525 Benefits of Sevelamer on Markers of Bone Turnover in Taiwanese Hemodialysis Patients Journal of the Formosan Medical Association = Taiwan Yi Zhi. Sep, 2010 | Pubmed ID: 20863994 Macrophage Wnt7b is Critical for Kidney Repair and Regeneration Proceedings of the National Academy of Sciences of the United States of America. Mar, 2010 | Pubmed ID: 20160075 Diagnosis of Primary Aldosteronism: Comparison of Post-captopril Active Renin Concentration and Plasma Renin Activity Clinica Chimica Acta; International Journal of Clinical Chemistry. May, 2010 | Pubmed ID: 20117105 Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis The American Journal of Pathology. Jan, 2010 | Pubmed ID: 20008127 Late Initiation of Renal Replacement Therapy is Associated with Worse Outcomes in Acute Kidney Injury After Major Abdominal Surgery Critical Care (London, England). 2009 | Pubmed ID: 19878554 Association of Kidney Function with Residual Hypertension After Treatment of Aldosterone-producing Adenoma American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. Oct, 2009 | Pubmed ID: 19628318 Comparison of Residual Renal Function in Patients Undergoing Twice-weekly Versus Three-times-weekly Haemodialysis Nephrology (Carlton, Vic.). Feb, 2009 | Pubmed ID: 19019171 Pericytes and Perivascular Fibroblasts Are the Primary Source of Collagen-producing Cells in Obstructive Fibrosis of the Kidney The American Journal of Pathology. Dec, 2008 | Pubmed ID: 19008372 Effect of Pentoxifylline in Addition to Losartan on Proteinuria and GFR in CKD: a 12-month Randomized Trial American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. Sep, 2008 | Pubmed ID: 18617301 Urinary Kallikrein Excretion is Related to Renal Function Change and Inflammatory Status in Chronic Kidney Disease Patients Receiving Angiotensin II Receptor Blocker Treatment Nephrology (Carlton, Vic.). Jun, 2008 | Pubmed ID: 18315702 Bradykinin Enhances Reactive Oxygen Species Generation, Mitochondrial Injury, and Cell Death Induced by ATP Depletion--a Role of the Phospholipase C-Ca(2+) Pathway Free Radical Biology & Medicine. Sep, 2007 | Pubmed ID: 17664134 Early Activation of Bradykinin B2 Receptor Aggravates Reactive Oxygen Species Generation and Renal Damage in Ischemia/reperfusion Injury Free Radical Biology & Medicine. Oct, 2006 | Pubmed ID: 17015177 Pentoxifylline Attenuates Tubulointerstitial Fibrosis by Blocking Smad3/4-activated Transcription and Profibrogenic Effects of Connective Tissue Growth Factor Journal of the American Society of Nephrology : JASN. Sep, 2005 | Pubmed ID: 15987746 YC-1-inhibited Proliferation of Rat Mesangial Cells Through Suppression of Cyclin D1-independent of CGMP Pathway and Partially Reversed by P38 MAPK Inhibitor European Journal of Pharmacology. Jul, 2005 | Pubmed ID: 15950964 The Renoprotective Potential of Pentoxifylline in Chronic Kidney Disease Journal of the Chinese Medical Association : JCMA. Mar, 2005 | Pubmed ID: 15813241 Pentoxifylline: a Potential Therapy for Chronic Kidney Disease Nephrology (Carlton, Vic.). Aug, 2004 | Pubmed ID: 15363050 Pentoxifylline Suppresses Renal Tumour Necrosis Factor-alpha and Ameliorates Experimental Crescentic Glomerulonephritis in Rats Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. May, 2004 | Pubmed ID: 14993492 Dual Regulation of Tumor Necrosis Factor-alpha-induced CCL2/monocyte Chemoattractant Protein-1 Expression in Vascular Smooth Muscle Cells by Nuclear Factor-kappaB and Activator Protein-1: Modulation by Type III Phosphodiesterase Inhibition The Journal of Pharmacology and Experimental Therapeutics. Jun, 2004 | Pubmed ID: 14978197 Expression of CX3CL1/fractalkine by Mesangial Cells in Vitro and in Acute Anti-Thy1 Glomerulonephritis in Rats Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. Dec, 2003 | Pubmed ID: 14605272 Pentoxifylline Inhibits Platelet-derived Growth Factor-stimulated Cyclin D1 Expression in Mesangial Cells by Blocking Akt Membrane Translocation Molecular Pharmacology. Oct, 2003 | Pubmed ID: 14500737 Intrahepatic Hemorrhage and Subcapsular Hematoma Developing in Acute Pancreatitis Hepato-gastroenterology. Mar-Apr, 2003 | Pubmed ID: 12749275 Tumor Necrosis Factor-alpha Stimulates Fractalkine Production by Mesangial Cells and Regulates Monocyte Transmigration: Down-regulation by CAMP Kidney International. Feb, 2003 | Pubmed ID: 12631113 Pentoxifylline Attenuated the Renal Disease Progression in Rats with Remnant Kidney Journal of the American Society of Nephrology : JASN. Dec, 2002 | Pubmed ID: 12444210 Topical Antifungal Treatment Cures Exit-site Fungal Infection American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. Oct, 2002 | Pubmed ID: 12324936 A Clinically Relevant Murine Model of Peritoneal Fibrosis by Dialysate and Catheters Yi-Ting Chen1,2,3, Shuei-Liong Lin1,2,3 1Department of Integrated Diagnostics & Therapeutics, National Taiwan University Hospital, 2Renal Division, Department of Internal Medicine, National Taiwan University Hospital, 3Graduate Institute of Physiology, National Taiwan University College of Medicine JoVE 63901 Immunologia e infezioni
A Clinically Relevant Murine Model of Peritoneal Fibrosis by Dialysate and Catheters Yi-Ting Chen1,2,3, Shuei-Liong Lin1,2,3 1Department of Integrated Diagnostics & Therapeutics, National Taiwan University Hospital, 2Renal Division, Department of Internal Medicine, National Taiwan University Hospital, 3Graduate Institute of Physiology, National Taiwan University College of Medicine JoVE 63901 Immunologia e infezioni