Selective Gene Silencing in the Choroid Plexus

June 16, 2023

Knockdown mirato dei geni nel plesso coroideo

ChP Knockdown specifico di A_2ARs con AAV2/5-shRNA e sistema Cre/LoxP

Yuwen Yang*¹, Chenxing Qi*¹, Lanxin Hu, Cheng Zheng, Xuhang Li, Wu Zheng, Yiyun Weng, Haiyan Lin⁴

¹State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital,Wenzhou Medical University, ²Department of Neurology,the First Affiliated Hospital of Wenzhou Medical University, ³Rehabilitation Medicine Center,The Second Affiliated Hospital of Wenzhou Medical University, ⁴Integrative & Optimized Medicine Research Center, China-USA Institute for Acupuncture and Rehabilitation,Wenzhou Medical University

Summary

Qui, descriviamo un metodo per alterare selettivamente le espressioni geniche nel plesso coroideo evitando qualsiasi impatto in altre aree cerebrali.

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