1Department of Microbiology and Immunology, College of Medicine,National Cheng Kung University, 2Department of Dermatology, National Cheng Kung University Hospital, College of Medicine,National Cheng Kung University, 3Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine,National Cheng Kung University, 4National Institute of Infectious Diseases and Vaccinology,National Health Research Institutes, 5Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine,National Cheng Kung University, 6Insititute of Basic Medical Sciences, College of Medicine,National Cheng Kung University, 7Department of Biochemistry and Molecular Biology, College of Medicine,National Cheng Kung University, 8Center of Applied Nanomedicine,National Cheng Kung University
Candida spp. ilaç direncinde minyon kolonilerin önemi tam olarak araştırılmamıştır. Antimikrobiyal fotodinamik tedavi (aPDT), ilaca dirençli mantar enfeksiyonlarına karşı umut verici bir strateji sunmaktadır. Bu çalışma, gül bengal aracılı aPDT’nin Candida glabrata’yı etkili bir şekilde deaktive ettiğini ve küçük kolonileri indükleyerek benzersiz bir prosedür sunduğunu göstermektedir.
