ACA Cell Biotech GmbH 2 articles published in JoVE Bioengineering Human Liver Spheroids from Peripheral Blood for Liver Disease Studies Anne-Kathrin Schott1, Ivan Zipančić2, Vicente Hernández-Rabaza2, Zorica A. Becker-Kojić1 1ACA CELL Biotech GmbH, 2Departamento Ciencias Biomédicas, Universidad Cardenal Herrera-CEU Here we present a non-genetic method to generate human autologous liver spheroids using mononuclear cells isolated from steady-state peripheral blood. Neuroscience GM-Free Generation of Blood-Derived Neuronal Cells Zorica A. Becker-Kojić1, Anne-Kathrin Schott1, Ivan Zipančić2, Vicente Hernández-Rabaza2 1ACA CELL Biotech GmbH, 2Departmento Ciencias Biomedicas, Universidad Cardenal Herrera-CEU We present a genetically modified-free (GM-free) method to obtain cells with a neuronal phenotype from reprogrammed peripheral blood cells. Activation of a signaling pathway linked to novel human GPI-linked protein reveals an efficient GM-free method for obtaining human pluripotent stem cells.