Sotera Defense Solutions 1 article published in JoVE Bioengineering Targeted Plasma Membrane Delivery of a Hydrophobic Cargo Encapsulated in a Liquid Crystal Nanoparticle Carrier Okhil K. Nag1, Jawad Naciri1, Eunkeu Oh2,3, Christopher M. Spillmann1, James B. Delehanty1 1Center for Biomolecular Science and Engineering, Naval Research Laboratory, 2Optical Sciences Division, Naval Research Laboratory, 3Sotera Defense Solutions A liquid crystal nanoparticle (LCNP) nanocarrier is exploited as a vehicle for the controlled delivery of a hydrophobic cargo to the plasma membrane of living cells.