Medtronic View Institution's Website 4 articles published in JoVE Medicine Evaluation of Capnography Sampling Line Compatibility and Accuracy when Used with a Portable Capnography Monitor Ruben D. Restrepo1, Ido Karpenkop2, Katherine E. Liu3 1Division of Respiratory Care, UT Health Science Center at San Antonio, 2Research and Development, OEM Engineering, Patient Monitoring, Medtronic, Jerusalem, 3Minimally Invasive Therapies Group, Scientific Communications, Medtronic, Minneapolis The goal of this study was to evaluate the accuracy of capnography sampling lines used in conjunction with a portable bedside capnography monitor. Sampling lines from 7 manufacturers were evaluated for tensile strength, rise time, and ETCO2 accuracy as a function of respiratory rate or supplemental oxygen flow rate. Medicine Testing the Efficacy of Pharmacological Agents in a Pericardial Target Delivery Model in the Swine Tinen L. Iles1, Brian Howard2, Stephen Howard3, Stephen Quallich2, Christopher Rolfes2, Eric Richardson4, Hanna R. Iaizzo5, Paul A. Iaizzo1 1Surgery, University of Minnesota, 2Biomedical Engineering, University of Minnesota, 3Medtronic, Inc., 4Bioengineering, Rice University, 5Pharmacy, University of Wisconsin We have developed a swine model for the target delivery of pharmacological agents within the pericardial space/fluid. Using this approach, the relative benefits of administered agents on induced atrial fibrillation, relative refractory periods and/or ischemic protection can be investigated. Medicine Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter Michael E. Rich1, Andrew Tseng2, Hae W. Lim3, Paul J. Wang4, Wilber W. Su1 1Department of Cardiovascular Medicine, Cavanagh Heart Center, Banner-University Medical Center, 2Mayo Medical School, Mayo Clinic, 3AF Solutions, Medtronic plc, 4Cardiology Division, Stanford University School of Medicine, Stanford University The goal of this study is to demonstrate the preferential location of transseptal puncture during a cryoballoon catheter ablation procedure for the treatment of atrial fibrillation. Medicine Direct Pressure Monitoring Accurately Predicts Pulmonary Vein Occlusion During Cryoballoon Ablation Ioanna Kosmidou1, Shannnon Wooden1, Brian Jones2, Thomas Deering1, Andrew Wickliffe1, Dan Dan1 1Department of Cardiac Electrophysiology, Piedmont Heart Institute, 2Cardiac Rhythm, Medtronic Inc. Effective pulmonary vein isolation utilizing a cryoballoon depends on complete pulmonary vein occlusion. The point of occlusion can be effectively predicted by direct analysis of pulmonary vein pressure waveform analysis during balloon inflation using a simple and reproducible technique.