All Protocols and Video Articles for scientific research | JoVE

Showing 301 - 312 of 565 videos for "Recessive Mutations"

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Journal (Developmental Biology)

Shifting Zebrafish Lethal Skeletal Mutant Penetrance by Progeny Testing

Elliott P. Brooks, James T. Nichols

¹Department of Craniofacial Biology,University of Colorado Anschutz Medical Campus

Journal (Genetics)

A Standard Methodology to Examine On-site Mutagenicity As a Function of Point Mutation Repair Catalyzed by CRISPR/Cas9 and SsODN in Human Cells

Natalia Rivera-Torres², Eric B. Kmiec²

¹Gene Editing Institute, Helen F. Graham Cancer Center and Research Institute,Christiana Care Health Services, ²Department of Medical Sciences,University of Delaware

Journal (Biology)

High-throughput Screening for Protein-based Inheritance in S. cerevisiae

James S. Byers, Daniel F. Jarosz²

¹Department of Developmental Biology,Stanford University School of Medicine, ²Department of Chemical and Systems Biology,Stanford University School of Medicine

Journal (Immunology and Infection)

Generation of Escape Variants of Neutralizing Influenza Virus Monoclonal Antibodies

Paul E. Leon², Teddy John Wohlbold², Wenqian He², Mark J. Bailey², Carole J. Henry, Patrick C. Wilson, Florian Krammer, Gene S. Tan

¹Department of Microbiology,Icahn School of Medicine at Mount Sinai, ²Graduate School of Biomedical Sciences,Icahn School of Medicine at Mount Sinai, ³The Department of Medicine, Section of Rheumatology, The Knapp Center for Lupus and Immunology Research,The University of Chicago

Journal (Genetics)

Primordial Germ Cell Transplantation for CRISPR/Cas9-based Leapfrogging in Xenopus

¹Department of Developmental and Cell Biology,University of California, Irvine

Journal (Medicine)

In Vivo Imaging of Cx3cr1^gfp/gfp Reporter Mice with Spectral-domain Optical Coherence Tomography and Scanning Laser Ophthalmoscopy

Despina Kokona, Joël Jovanovic, Andreas Ebneter, Martin S. Zinkernagel

¹Department of Ophthalmology and Department of Clinical Research,Bern University Hospital and University of Bern

Journal (Cancer Research)

Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure

Toshimitsu Yamaoka, Motoi Ohba, Satoru Arata², Tohru Ohmori

¹Institute of Molecular Oncology,Showa University, ²Center for Biotechnology,Showa University

Journal (Cancer Research)

A Genetically Engineered Mouse Model of Sporadic Colorectal Cancer

Alexander M. Betzler, Susan Kochall, Linda Blickensdörfer, Sebastian A. Garcia, May-Linn Thepkaysone, Lahiri K. Nanduri, Michael H. Muders, Jürgen Weitz^4,5, Christoph Reissfelder, Sebastian Schölch^4,5

¹Department of Gastrointestinal, Thoracic and Vascular Surgery, Medizinische Fakultät Carl Gustav Carus,Technische Universität Dresden, ²Department of General, Gastrointestinal and Transplant Surgery,University of Heidelberg, ³Department of Pathology, Medizinische Fakultät Carl Gustav Carus,Technische Universität Dresden, ⁴German Cancer Consortium (DKTK), ⁵German Cancer Research Center (DKFZ)

Journal (Medicine)

Investigating von Willebrand Factor Pathophysiology Using a Flow Chamber Model of von Willebrand Factor-platelet String Formation

Alison Michels, Laura L. Swystun, Jeffrey Mewburn, Silvia Albánez, David Lillicrap

¹Department of Pathology and Molecular Medicine,Queen's University, ²Department of Medicine,Queen's University

Journal (Bioengineering)

A Protocol for Multiple Gene Knockout in Mouse Small Intestinal Organoids Using a CRISPR-concatemer

Alessandra Merenda², Amanda Andersson-Rolf², Roxana C. Mustata, Taibo Li, Hyunki Kim, Bon-Kyoung Koo²

¹Wellcome Trust - Medical Research Council Stem Cell Institute,University of Cambridge, ²Department of Genetics,University of Cambridge, ³Department of Pathology,Yonsei University College of Medicine

Journal (Genetics)

Selection-dependent and Independent Generation of CRISPR/Cas9-mediated Gene Knockouts in Mammalian Cells

Erin L. Sternburg, Kristen C. Dias, Fedor V. Karginov

¹Cell Biology and Neuroscience,University of California, Riverside

Journal (Cancer Research)

Induction and Diagnosis of Tumors in Drosophila Imaginal Disc Epithelia

Kenta Morimoto², Yoichiro Tamori

¹Structural Biology Center, National Institute of Genetics and Department of Genetics, School of Life Science,SOKENDAI, ²Graduate School of Media and Governance,Keio University

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