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Combining Peripheral Nerve Grafting and Matrix Modulation to Repair the Injured Rat Spinal Cord
JoVE Journal
Biologia
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JoVE Journal Biologia
Combining Peripheral Nerve Grafting and Matrix Modulation to Repair the Injured Rat Spinal Cord
DOI:

20:14 min

November 20, 2009

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Capitoli

  • 00:00Titolo
  • 01:09Introduction
  • 01:43Transection of the Peripheral Nerve (PN) and Removal of PN Segment
  • 08:58Cervical Hemisection Injury and Transplantation of PN
  • 13:20Treating the Area of Injury with Chondroitinase
  • 17:07Representative Electrophysiological and Immunocytochemical Results
  • 19:41Conclusion

Summary

Traduzione automatica

Traumatic injury to the spinal cord disrupts communication with the brain. To restore lost connectivity we utilize a peripheral nerve graft to provide a substratum for regenerating fibers in combination with neurotrophic factors and matrix-modulating enzymes to remove inhibitory molecules to promote long distance growth.

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