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Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease
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Biologia
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JoVE Journal Biologia
Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease

DOI:
10.3791/1437-v

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09:10 min

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January 20, 2010

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, , , , ,
1Transplant and Stem Cell Immunobiology Lab (TSI),University Heart Center Hamburg, 2CVRC,University Hospital Hamburg, 3Department of CT Surgery,Stanford University School of Medicine

Capitoli

  • 00:00Titolo
  • 00:56Introduction
  • 01:44Preparing the Donor Trachea
  • 03:09Heterotopic Tracheal Transplantation
  • 04:59Orthotopic Tracheal Transplantation
  • 08:08Development of Obliterative Airway Disease (OAD) in Both Models
  • 08:38Conclusion

Summary

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This video shows and compares two experimental models to study the development of obliterative airway disease (OAD) in mice, the heterotopic and orthotopic tracheal transplantation model.

Tags

Heterotopic Tracheal TransplantationOrthotopic Tracheal TransplantationMice ModelsObliterative Airway DiseaseLung TransplantationsPathophysiology Of OADTreatment Of OADPrevention Of OADAnimal ModelsAdvantages And Limitations Of Tracheal Transplantation ModelsGreater OmentumEnd-to-end AnastomosisObliterative LesionsHistology

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