Low-stress Route Learning Using the Lashley III Maze in Mice

Amanda Bressler; David Blizard; Anne Andrews

doi:10.3791/1786

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Neuroscienze

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Low-stress Route Learning Using the Lashley III Maze in Mice

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Neuroscienze

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JoVE Journal Neuroscienze

Low-stress Route Learning Using the Lashley III Maze in Mice

DOI:

10.3791/1786-v

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09:14 min

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May 22, 2010

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Amanda Bressler, David Blizard, Anne Andrews^4,5,6

¹Department of Chemistry,Pennsylvania State University, ²Center for Developmental and Health Genetics,Pennsylvania State University, ³Department of Veterinary and Biomedical Sciences,Pennsylvania State University, ⁴Huck Institute of the Life Sciences,Pennsylvania State University, ⁵California NanoSystems Institute,University of California, Los Angeles, ⁶Semel Institute of Neuroscience and Human Behavior,University of California, Los Angeles

Capitoli

00:00Titolo
00:50Introduction
01:08Part 1 – Preparing the Maze
03:03Part 2 – Maze Testing
06:32Representative Behavioral Results
08:45Conclusion

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The Lashley III maze is a route-learning task that does not rely on aversive stimuli or visual cues. It is thus a highly attractive option for evaluating learning and memory, especially in aging mice or otherwise where stress is a consideration.

Low-stress Route Learning Using the Lashley III Maze in Mice

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