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Real-Time Measurements of Calcium and Contractility Parameters in hiPSC-CMs

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Medidas de contractilidad en hiPSC-MCs

JoVE Journal
Biologia

This content is Free Access.

JoVE Journal Biologia

Contractility Measurements in hiPSC-CMs

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Medidas de contractilidad en hiPSC-MCs

Real-Time Measurements of Calcium and Contractility Parameters in hiPSC-CMs

DOI:

10.3791/200096-v

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02:30 min

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May 26, 2023

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Rafeeh Dinani², Emmy Manders^2,3, Michiel Helmes^2,3, Lili Wang, Bjorn C. Knollmann, Diederik W. D. Kuster², Jolanda van der Velden²

¹Division of Physiology, Amsterdam UMC,Vrije University, ²Heart Failure & Arrhythmias,Amsterdam Cardiovascular Sciences, ³CytoCypher BV, ⁴Division of Clinical Pharmacology,Vanderbilt School of Medicine

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Keywords: Contractility HiPSC-CMs Optics-based Measurement System Tyrode’s Solution Climate Control Lid Cell Finder Synchronized Contraction And Relaxation Baseline Measurements Stressor Compound Automatic Measurement

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