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Harnessing iPSC-Derived iTenocytes for Effective Cell-Based Therapy

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Mekanisk belastning af iMSC^SCX+ i en 2D-bioreaktor til cyklisk strækning

JoVE Journal
Bioingegneria

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JoVE Journal Bioingegneria

Mechanical Loading of iMSC^SCX+ in a 2D Bioreactor for Cyclic Stretching

Mekanisk belastning af iMSC^SCX+ i en 2D-bioreaktor til cyklisk strækning

Harnessing iPSC-Derived iTenocytes for Effective Cell-Based Therapy

DOI:

10.3791/200708-v

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03:07 min

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March 01, 2024

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Victoria Yu^2,3, Angela Papalamprou^2,3, Dmitriy Sheyn^2,3,4,5

¹Orthopaedic Stem Cell Research Laboratory,Cedars-Sinai Medical Center, ²Board of Governors Regenerative Medicine Institute,Cedars-Sinai Medical Center, ³Department of Biomedical Sciences,Cedars-Sinai Medical Center, ⁴Department of Orthopedics,Cedars-Sinai Medical Center, ⁵Department of Surgery,Cedars-Sinai Medical Center

Tags

IMSCSCX+2D Bioreactor Cyclic Stretching Mechanical Loading Fibronectin Scleraxis-positive Induced Mesenchymal Stromal Cells Uniaxial Tension Sinusoidal Strain Cell Organization Phalloidin Staining Tenogenic Genes Collagen Deposition

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Generering af inducerede pluripotente stamcelleafledte iTenocytter via kombineret scleraksoverekspression og 2D uniaxial spænding

Mekanisk belastning af iMSC^SCX+ i en 2D-bioreaktor til cyklisk strækning

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