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Tri-layered Electrospinning to Mimic Native Arterial Architecture using Polycaprolactone, Elastin, and Collagen: A Preliminary Study
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Tri-layered Electrospinning to Mimic Native Arterial Architecture using Polycaprolactone, Elastin, and Collagen: A Preliminary Study

Tri-layered Electrospinning to Mimic Native Arterial Architecture using Polycaprolactone, Elastin, and Collagen: A Preliminary Study

DOI:
10.3791/2084-v

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10:47 min

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January 04, 2011

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, , , ,
1Department of Biomedical Engineering,Virginia Commonwealth University, 2Department of Anatomy and Neurobiology,Virginia Commonwealth University, 3Department of Cardiovascular Surgery,University Hospital of Geneva

Capitoli

  • 00:05Titolo
  • 00:58Introduction
  • 01:16Electrospinning of Arterial Materials
  • 04:41Evaluation of Electrospun Materials
  • 08:30Exlectrospinning of Native Arterial Architecture
  • 10:11Conclusion

Summary

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The aim of this study was to mimic the native three layered architecture of the arterial wall. To accomplish this, electrospinning was employed with the use of a 3-1 (input-output) nozzle and blends of polycaprolactone, elastin, and collagen.

Tags

Tri-layered ElectrospinningNative Arterial ArchitecturePolycaprolactoneElastinCollagenMechanical PropertiesMulti-layered Electrospun ConduitUniaxial Tensile TestingDynamic ComplianceSuture RetentionBurst StrengthModulus RangeCircumferential Wall StressMathematical Modeling

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