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Colon Ascendens Stent Peritonitis (CASP) – a Standardized Model for Polymicrobial Abdominal Sepsis
JoVE Journal
Immunologia e infezioni
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JoVE Journal Immunologia e infezioni
Colon Ascendens Stent Peritonitis (CASP) – a Standardized Model for Polymicrobial Abdominal Sepsis

Colon Ascendens Stent Peritonitis (CASP) – a Standardized Model for Polymicrobial Abdominal Sepsis

DOI:
10.3791/2299-v

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06:45 min

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December 18, 2010

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, , , , , , ,
1Department of Surgery,University of Greifswald

Capitoli

  • 00:05Titolo
  • 01:02Preparation of the Mouse
  • 01:21CASP Operation
  • 03:12Postoperative Care
  • 03:26CASPI
  • 04:06Postoperative Care
  • 04:27CASP and CASPI Clinical Outcomes
  • 06:16Conclusion

Summary

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The Colon Ascendens Stent Peritonitis (CASP) is a highly standardized model for polymicrobial abdominal sepsis in rodents. This article describes the surgical procedure of CASP. The CASP model and its variants allow the systematic investigation of various problems concerning the subject of sepsis.

Tags

Colon Ascendens Stent PeritonitisCASPPolymicrobial Abdominal SepsisSepsisAnimal ModelsTherapeutic ApproachesScientific QuestionsRodent ModelStent InsertionIntestinal BacteriaPeritonitisBacteraemiaOrgan InfectionCytokinesLethality ControlCASPI VariantSeptic Focus RemovalClinical PracticeLearnable ModelReproducible ModelClinical CourseImmunologyInfectiologySurgery

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