Rivista
/
Neuroscienze
/
Studying the Integration of Adult-born Neurons
JoVE Journal
Neuroscienze
This content is Free Access.
JoVE Journal Neuroscienze
Studying the Integration of Adult-born Neurons

Studying the Integration of Adult-born Neurons

DOI:
10.3791/2548-v

•

09:00 min

•

March 25, 2011

•

, ,
1Department of Neurobiology & Behavior,State University of New York at Stony Brook

Capitoli

  • 00:05Titolo
  • 01:03Introduction
  • 01:35Virus Injection
  • 05:16Electrophysiological Experiments
  • 07:24Results: Identification and Neuronal Activity of Newborn Neurons in the Dentate Gyrus
  • 08:36Conclusion

Summary

Traduzione automatica

Traduzione automatica

A way to study the integration of newborn dentate granule cells in adult animals is described. This technique uses an engineered retrovirus to label newborn neurons, followed by electrophysiological recordings to determine in vivo functional integration.

Tags

IntegrationAdult-born NeuronsNeurogenesisSub-ventricular ZoneLateral VentricleSub-granular ZoneHippocampal Dentate GyrusBrain DisordersEpilepsySchizophreniaDepressionAnxietyAberrant Neuron IntegrationEtiologyNew TherapiesFate SpecificationMigrationSynaptic IntegrationMaturationGABAergic InputGlutamatergic InputCircuit FormationDentate Granule CellsViral TechniqueCell Birth DateLineageMorphologySynaptogenesis

Article

Embed

AGGIUNGI ALLA PLAYLIST

Usage Statistics

Video correlati

check_url/it/2548?article_type=v

In utero Electroporation followed by Primary Neuronal Culture for Studying Gene Function in Subset of Cortical Neurons
check_url/it/2548?article_type=v

Selective Viral Transduction of Adult-born Olfactory Neurons for Chronic in vivo Optogenetic Stimulation
check_url/it/2548?article_type=v

The Specification of Telencephalic Glutamatergic Neurons from Human Pluripotent Stem Cells
check_url/it/2548?article_type=v

Fast Micro-iontophoresis of Glutamate and GABA: A Useful Tool to Investigate Synaptic Integration
check_url/it/2548?article_type=v

Differential Labeling of Cell-surface and Internalized Proteins after Antibody Feeding of Live Cultured Neurons
check_url/it/2548?article_type=v

A Microbiomechanical System for Studying Varicosity Formation and Recovery in Central Neuron Axons
check_url/it/2548?article_type=v

In Vivo Two-photon Imaging of Cortical Neurons in Neonatal Mice
check_url/it/2548?article_type=v

An In Vitro Model for Studying Tau Aggregation Using Lentiviral-mediated Transduction of Human Neurons
check_url/it/2548?article_type=v

Wireless Electrophysiological Recording of Neurons by Movable Tetrodes in Freely Swimming Fish
check_url/it/2548?article_type=v

Studying Pre-formed Fibril Induced α-Synuclein Accumulation in Primary Embryonic Mouse Midbrain Dopamine Neurons

Read Article