Waiting
Elaborazione accesso...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Medicine / Establishment and Propagation of Human…
JoVE Journal
Medicine

This Contenuto is Open Access.

JoVE Journal Medicine
Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice
 
Click here for the English version

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice

Article DOI: 10.3791/2644-v • 07:56 min • August 4th, 2011
August 4th, 2011 •
1,2, 2,3, 2,3, 4, 2,3, *2,3,5,6, *4,5,7
1Interdepartmental Program in Translational Biology & Molecular Medicine, Baylor College of Medicine, 2Texas Children's Cancer Center, Baylor College of Medicine, 3Department of Pediatrics, Baylor College of Medicine, 4Department of Pathology, The Methodist Hospital Research Institute, 5Department of Ophthalmology, Retinoblastoma Center of Houston, 6Baylor College of Medicine, Center for Cell and Gene Therapy, 7Center for Cell and Gene Therapy, Baylor College of Medicine
* These authors contributed equally

Capitoli

Riepilogo
Automatic Translation

Please note that all translations are automatically generated.

Click here for the English version.

A method is described to propagate human retinoblastoma tumors in mice. Tumor cells are directly injected into the eyes of immune deficient mice. Secondary tumors have been successfully established using both cells directly harvested from human tumors and cultured tumorspheres.

Tags

Establishment Propagation Human Retinoblastoma Tumors Immune Deficient Mice Cultured Tumorspheres Cellular Phenotypes New Tumors Formation Rag2-/- Immune Deficient Mice Vitreous Cavity Murine Eyes Tumorspheres In Vitro Three Passages Continuing Source Human Retinoblastoma Tissue Wesley S. Bond Lalita Wadhwa
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter