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Gene Transfer for Ischemic Heart Failure in a Preclinical Model
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JoVE Journal Medicina
Gene Transfer for Ischemic Heart Failure in a Preclinical Model

Gene Transfer for Ischemic Heart Failure in a Preclinical Model

DOI:
10.3791/2778-v

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07:35 min

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May 15, 2011

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, , , , ,
1Cardiovascular Research Center,Mount Sinai School of Medicine

Capitoli

  • 00:05Titolo
  • 01:15Introduction
  • 01:44Myocardial Infarct Creation
  • 04:30Virus Injection
  • 05:58Representative Results
  • 07:04Conclusion

Summary

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A method of gene transfer for the treatment of ischemic heart failure is described using a swine model of myocardial infarction. Our simple and reproducible method enables us to readily evaluate the efficacy of various gene transfers with a very simple and reproducible way.

Tags

Gene TransferIschemic Heart FailurePreclinical ModelEmerging TechnologiesCardiac DiseasesViral VectorsGene TherapyAnimal ModelSwine ModelMyocardial InfarctionHeart RemodelingIntracoronary InjectionNitroglycerine InfusionGene ExpressionTherapeutic Candidates

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