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Bioengineering

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JoVE Journal Bioengineering
Alginate Hydrogels for Three-Dimensional Organ Culture of Ovaries and Oviducts
 
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Alginate Hydrogels for Three-Dimensional Organ Culture of Ovaries and Oviducts

Article DOI: 10.3791/2804-v • 07:13 min • June 20th, 2011
June 20th, 2011 •
*1, *1, *1, 1, 1
1Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago
* These authors contributed equally

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Culture of normal cells in their three-dimensional context represents an alternative method to study early events required for cellular transformation and tumorigenesis. This method is used to grow normal ovarian and oviductal cells to study early events in ovarian cancer formation.

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Alginate Hydrogels Three-dimensional Organ Culture Ovaries Oviducts Ovarian Cancer Mortality Rate Cell Type Of Origin Ovarian Surface Epithelium Fallopian Tube Fimbriae Primary Culture In Vitro Culture Biomarkers Animal Models Prevention Strategies Alginate Hydrogel Culture Plasmid DNA SiRNA Small Molecules Scalpel Cuts Ovulation Modeling OSE Proliferation Plastic Surfaces
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