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Journal / Biology / Competitive Genomic Screens of Barcoded Yeast…
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Biology

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JoVE Journal Biology
Competitive Genomic Screens of Barcoded Yeast Libraries
 
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Competitive Genomic Screens of Barcoded Yeast Libraries

Article DOI: 10.3791/2864-v • 12:00 min • August 11th, 2011
August 11th, 2011 •
*1,2, *2,3, *4, 1,2, 5, 2,3, 2,6, 1,2,3
1Banting and Best Department of Medical Research and Department of Molecular Genetics, University of Toronto, 2Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 3Donnelly Sequencing Centre, University of Toronto, 4Genetics and Molecular Biology Branch, National Human Genome Research Institute, NIH, 5Stanford Genome Technology Center, Stanford School of Medicine, Stanford University, 6Department of Pharmaceutical Sciences, University of Toronto
* These authors contributed equally

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We have developed comprehensive, unbiased genome-wide screens to understand gene-drug and gene-environment interactions. Methods for screening these mutant collections are presented.

Tags

Competitive Genomic Screens Barcoded Yeast Libraries Next Generation Sequencing Genome Sequences Gene Function Deletion Mutants High-throughput Phenotyping DNA Tags Barcodes Mutant Fitness Transposon Disruption-barcoding Approach Candida Albicans Barcoded Disruption
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