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椎管内针对肌萎缩性脊髓侧索硬化症和外伤性脊髓损伤颈腹角细胞移植

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Medicina

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JoVE Journal Medicina

Intraspinal Cell Transplantation for Targeting Cervical Ventral Horn in Amyotrophic Lateral Sclerosis and Traumatic Spinal Cord Injury

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椎管内针对肌萎缩性脊髓侧索硬化症和外伤性脊髓损伤颈腹角细胞移植

DOI:

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10:49 min

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September 18, 2011

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Angelo C. Lepore

¹Department of Neuroscience,Thomas Jefferson University Medical College

Capitoli

00:05Titolo
01:29Preparation for Transplant Surgery
03:51Transplantation of Glial Progenitor Cells
09:49Representative Results of Glial Cell Transplantation Experiments
10:33Conclusion

Summary

Traduzione automatica

神经前体移植是一种很有前途的战略，保护和/或更换丢失/功能失调颈椎膈运动神经元在脊髓损伤（SCI）和运动神经元症，肌萎缩边音硬化症（ALS）。我们提供了一个细胞传递到脊髓型颈椎病ALS和SCI的啮齿类动物模型腹角的协议。

Tags

Intraspinal Cell Transplantation Targeting Cervical Ventral Horn Amyotrophic Lateral Sclerosis Traumatic Spinal Cord Injury Respiratory Compromise Phrenic Motor Neuron Loss Motor Neuron Disorder Rapid Degeneration Upper And Lower Motor Neurons Respiratory Paralysis Diaphragm Innervation Familial Cases Cu/Zn Superoxide Dismutase 1 Gene SOD1 Gene Mutations Transgenic Mice And Rats Animal Models Spinal Cord Injury Heterogeneous Conditions

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