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Combination Radiotherapy in an Orthotopic Mouse Brain Tumor Model
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JoVE Journal Medicina
Combination Radiotherapy in an Orthotopic Mouse Brain Tumor Model

Combination Radiotherapy in an Orthotopic Mouse Brain Tumor Model

DOI:
10.3791/3397-v

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08:02 min

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March 06, 2012

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,
1Radiation Oncology Branch,National Cancer Institute

Capitoli

  • 00:05Titolo
  • 01:09Preparing Cells for Injection
  • 02:49Animal Preparation
  • 03:50Surgery
  • 06:31Implant Radiation
  • 07:01Post-injection Evaluations
  • 07:41Conclusion

Summary

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The purpose of this article is to describe the use of an orthotopic glioblastoma model for chemoradiation studies. This article will go though cell processing, implanting, and radiotherapy of the mouse using an intracranial model.

Tags

Combination RadiotherapyOrthotopic Mouse Brain Tumor ModelGlioblastoma MultiformeTumor InvasionIntracerebral InoculationOrthotopic ModelsStereotaxic InjectionCell SuspensionCraniotomy ProcedureSurgical PlaneInjectable AnestheticStereotaxic JigBregmaCraniotomy LocationDepth Of InjectionCell LineTreatment

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