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The Use of Cystometry in Small Rodents: A Study of Bladder Chemosensation
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JoVE Journal Medicina
The Use of Cystometry in Small Rodents: A Study of Bladder Chemosensation

The Use of Cystometry in Small Rodents: A Study of Bladder Chemosensation

DOI:
10.3791/3869-v

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08:08 min

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August 21, 2012

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, , , , , , , , ,
1Laboratory of Experimental Urology, Department of Development and Regeneration,KU Leuven, Belgium, 2Laboratory for Ion Channel Research, Department of Cellular and Molecular Medicine,KU Leuven, Belgium, 3TRP Research Platform Leuven (TRPLe),KU Leuven, Belgium

Capitoli

  • 00:05Titolo
  • 01:15Preparations for the Surgery
  • 02:02Implanting the Bladder Catheter
  • 04:21Cystometry
  • 05:35Representative Results
  • 07:32Conclusion

Summary

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Traduzione automatica

Cystometry is an efficient technique to measure bladder function of small animals in vivo. The bladder is continuously infused at rates controlled through an intravesical catheter, whereas the urethra is left free for micturition. This allows for repetitive filling and emptying of the bladder, while intravesical pressure and voided volume are recorded.

Tags

CystometrySmall RodentsBladder ChemosensationLower Urinary TractUrotheliumNoxious ChemicalsTRPV1 AgonistCapsaicinNeurogenic Bladder OveractivityChemosensory OrganClinical ResearchAnimal ModelsIntravesical PressureLaparotomy

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