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Extinction Training During the Reconsolidation Window Prevents Recovery of Fear
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Capitoli
- 00:05Titolo
- 01:43Fear Assessment with Skin Conductance Response (SCR) – Electrode Application & Recording
- 03:20Fear Induction with Mild Electric Shock Stimulation – Electrode Application & Work-up Procedure
- 04:35Day 1 – Acquisition
- 06:42Day 2 – Reactivation & Exctinction Training
- 08:30Day 3 – Spontaneous Fear Recovery Assay
- 09:12Results: Acquisition, Extinction and Spontaneous Recovery (SR) in an Individual Subject
- 10:43Conclusion
Conditioned fear can be diminished through an inhibitory process called extinction, but can resurface under conditions such as the passage of time or exposure to stress. Our protocol presents a novel way of preventing fear recovery by introducing extinction during the reconsolidation window (the re-storage phase of a reactivated memory).
Tags
Extinction TrainingReconsolidation WindowFear PreventionFear RecoveryPavlovian Fear-conditioning ParadigmsConditioned StimulusUnconditioned StimulusConditioned ResponseExtinction TrainingInhibitory LearningFear MemorySpontaneous Recovery Of FearStress-induced FearContextual Fear ResurfacingEmotional Memory ModificationMemory Reactivation
