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En<em> In vitro</em> Co-infeksjon modell for å studere<em> Plasmodium falciparum</em>-HIV-1 interaksjoner i Human Primary monocytt-deriverte immunceller
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Capitoli
- 00:05Titolo
- 01:45Plasmodium falciparum-infected Red Blood Cell (iRBC) Purification
- 02:35Exposure of Monocyte-derived Macrophages (MDM) to Plasmodium falciparum
- 03:40Infection of MDM with a Fully Replicative HIV-1
- 04:44Infection of MDM with Single Cycle Virus Encoding Luciferase
- 05:56Results: Exposure of P. falciparum to MDM Decreases their Susceptibility to HIV-1 Infection
- 07:16Conclusion
Vi har utviklet en<em> In vitro</em> Malaria-HIV-1 co-infeksjon modell for å studere virkningen av<em> Plasmodium falciparum</em> På HIV-1 replicative syklus i menneskets primære monocytt-deriverte makrofager. Dette allsidige systemet kan enkelt tilpasses andre primære celletyper utsatt for HIV-1 infeksjon.
Tags
In Vitro Co-infection ModelPlasmodium FalciparumHIV-1 InteractionsHuman Primary Monocyte-derived Immune CellsMalariaHIV-1Co-infectionsDisease ProgressionTransmissionImmunological MechanismsSoluble Malarial AntigensHIV-1 InfectionReactivationImmune CellsP. Falciparum Schizont Stage ParasitesPeripheral Blood Mononuclear Cells
