/
/
En<em> In vitro</em> Co-infektion modell för att studera<em> Plasmodium falciparum</em>-HIV-1 Interactions in Human primära monocyt-härledda Immunceller
This content is Free Access.
Capitoli
- 00:05Titolo
- 01:45Plasmodium falciparum-infected Red Blood Cell (iRBC) Purification
- 02:35Exposure of Monocyte-derived Macrophages (MDM) to Plasmodium falciparum
- 03:40Infection of MDM with a Fully Replicative HIV-1
- 04:44Infection of MDM with Single Cycle Virus Encoding Luciferase
- 05:56Results: Exposure of P. falciparum to MDM Decreases their Susceptibility to HIV-1 Infection
- 07:16Conclusion
Vi har utvecklat ett<em> In vitro</em> Malaria-HIV-1-infektion modell för att studera effekterna av<em> Plasmodium falciparum</em> I HIV-1-replikativa cykeln i humana primära monocythärledda makrofager. Denna mångsidiga system kan enkelt anpassas till andra primära celltyper mottagliga för HIV-1-infektion.
Tags
In Vitro Co-infection ModelPlasmodium FalciparumHIV-1 InteractionsHuman Primary Monocyte-derived Immune CellsMalariaHIV-1Co-infectionsDisease ProgressionTransmissionImmunological MechanismsSoluble Malarial AntigensHIV-1 InfectionReactivationImmune CellsP. Falciparum Schizont Stage ParasitesPeripheral Blood Mononuclear Cells
