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Capitoli
- 00:05Titolo
- 01:20Acclimation to Handling for Intranasal Dosing to Awake Mice
- 04:15Intranasal Delivery of Drug to Awake Mice
- 05:57General Animal Handling Techniques for Acclimation and Intranasal Delivery of Drug to Awake Mice
- 06:34Conclusion
A method to intranasally administer drugs to awake mice for the purpose of targeting the brain is described. This method allows for repeat dosing over long periods using intranasal administration of drug without anesthesia, and nose-to-brain delivery with minimal systemic exposure.
