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Three-dimensional Imaging of Nociceptive Intraepidermal Nerve Fibers in Human Skin Biopsies
 

Three-dimensional Imaging of Nociceptive Intraepidermal Nerve Fibers in Human Skin Biopsies

Article DOI: 10.3791/50331-v • 11:22 min • April 29th, 2013
April 29th, 2013 •
1, 1, 1, 2, 1
1Department of Neurology, University of Michigan, 2Department of Internal Medicine, University of Michigan

Capitoli

Riepilogo
Automatic Translation

In order to study the changes of nociceptive intraepidermal nerve fibers (IENFs) in painful neuropathies (PN), we developed protocols that could directly examine three-dimensional morphological changes observed in nociceptive IENFs. Three-dimensional analysis of IENFs has the potential to evaluate the morphological changes of IENF in PN.

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Keywords: 3D Imaging Nociceptive Intraepidermal Nerve Fibers Skin Biopsy Peripheral Polyneuropathy PGP TrkA Confocal Microscopy Neuropathy
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