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组织工程生物反应器的双轴机械装载设计

JoVE Journal
Bioingegneria

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JoVE Journal Bioingegneria

Design of a Biaxial Mechanical Loading Bioreactor for Tissue Engineering

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组织工程生物反应器的双轴机械装载设计

DOI:

10.3791/50387-v

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08:04 min

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April 25, 2013

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Bahar Bilgen², Danielle Chu, Robert Stefani, Roy K. Aaron²

¹Department of Orthopaedics,The Warren Alpert Brown Medical School of Brown University and the Rhode Island Hospital, ²Center for Restorative and Regenerative Medicine,VA Medical Center, Providence, RI, ³University of Texas Southwestern Medical Center

Capitoli

00:05Titolo
01:22Biaxial Loading Bioreactor Design
03:35Immobilization of Samples With Agarose
04:38Mechanical Loading of Tissue Constructs
06:25Results: Mechanical Loading Alters Extracellular Matrix Depositing in Tissue Engineered Cartilage
07:44Conclusion

Summary

Traduzione automatica

我们设计了一种新型的机械负荷生物反应器可应用于单轴或双轴机械应变移植到关节软骨缺损的软骨生物复合材料之前。

Tags

Biaxial Mechanical Loading Bioreactor Cartilage Constructs Uniaxial Loading Biaxial Loading Stepper Motor Actuators Closed-loop Stepper Motor Driver Micro-stepping Linear Optical Encoders Nanopositioning Precision Miniature Load Cell Force Feedback Mechanical Testing

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