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Assessment of Cardiac Function and Myocardial Morphology Using Small Animal Look-locker Inversion Recovery (SALLI) MRI in Rats
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Assessment of Cardiac Function and Myocardial Morphology Using Small Animal Look-locker Inversion Recovery (SALLI) MRI in Rats

Assessment of Cardiac Function and Myocardial Morphology Using Small Animal Look-locker Inversion Recovery (SALLI) MRI in Rats

DOI:
10.3791/50397-v

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08:41 min

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July 19, 2013

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, , , , , , ,
1Congenital Heart Disease and Pediatric Cardiology,German Heart Institute Berlin, 2Internal Medicine – Cardiology,German Heart Institute Berlin, 3Philips Health Care

Capitoli

  • 00:05Titolo
  • 01:14Tail Vein Cannula Insertion and Positioning of the Electrodes
  • 02:19Positioning of Animal and Scan Protocol
  • 04:30Image Reconstruction
  • 05:08Results: Small Animal Look-Locker Inversion Recovery (SALLI) MRI
  • 08:21Conclusion

Summary

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Contrast enhanced cardiac magnetic resonance (CMR) imaging allows comprehensive in vivo assessment of the heart in small animal models of cardiovascular disease. Here we detail the procedures to perform CMR imaging, reconstruction and analysis using Small Animal Lock-Locker Inversion Recovery (SALLI) in rats.

Tags

Cardiac FunctionMyocardial MorphologySmall AnimalLook-Locker Inversion RecoverySALLIMRIRatsT1 MappingContrast Agent KineticsDiffuse Myocardial ProcessesInterstitial FibrosisEdemaCine ImagingLate Gadolinium EnhancementSmall Animal Cardiac MRI

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