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平移血管复合同种异体移植（VCA）研究一种改进的异位猪后肢移植模型
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Medicina
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JoVE Journal Medicina
A Modified Heterotopic Swine Hind Limb Transplant Model for Translational Vascularized Composite Allotransplantation (VCA) Research
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平移血管复合同种异体移植（VCA）研究一种改进的异位猪后肢移植模型

DOI:
10.3791/50475-v

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09:09 min

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October 14, 2013

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, , , , , , , , , ,
1Plastic and Reconstructive Surgery,Johns Hopkins University School of Medicine

Capitoli

  • 00:05Titolo
  • 02:06Osteomyocutaneous Limb Allograft Harvest from Donor Pig
  • 04:23Recipient Hind Limb Allotransplantation
  • 07:17Results: Vascularized Composite Allotransplantation
  • 07:50Conclusion

Summary

Traduzione automatica

Traduzione automatica

血管化复合Allotransplantations（VCA）已成为临床现实。然而，VCA的广泛临床应用是由慢性多药免疫抑制的限制。作者提出一个可靠和可重复的大动物模型来翻译新型免疫调节策略，可以最大限度地减少或消除潜在的免疫抑制的VCA的需要。

Tags

Modified Heterotopic Swine Hind Limb TransplantVascularized Composite Allotransplantation (VCA)Translational ResearchImmunomodulationImmunosuppressionLarge Animal ModelOsteomyocutaneous FlapFemoral Vascular PedicleVascularized Bone Marrow TransplantImmune Monitoring

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